83540-97-0Relevant articles and documents
Preparation of enantiopure butane-2,3-diacetals of glycolic acid and alkylation reactions leading to α-hydroxyacid and amide derivatives
Ley, Steven V.,Diez, Elena,Dixon, Darren J.,Guy, Richard T.,Michel, Patrick,Nattrass, Gillian L.,Sheppard, Tom D.
, p. 3608 - 3617 (2007/10/03)
The preparation of butane-2,3-diacetal protected glycolic acid and related systems is described together with highly selective alkylation reactions of (R,R) and (S,S) butanediacetal protected glycolic acid. These compounds are readily deprotected to give
Synthesis of unnatural (R)-malates from L-tartrates
Rho, Ho-Sik
, p. 843 - 847 (2007/10/03)
The cyclic thionocarbonates of L-tartrates were cleanly converted to (R)-malates by treating with magnesium iodide or magnesium and iodine.
Ruthenium-catalyzed production of cyclic sulfates
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, (2008/06/13)
A ruthenium catalyzed method to synthesize cyclic sulfate compounds from the corresponding cyclic sulfites, and the cyclic sulfate reaction products obtained by this method. These cyclic sulfates further react with selected nucleophiles to give various substituted products. The method is an efficient means for the synthesis of chiral building blocks from tartaric acid enantiomers in high yields using an overall two-stage, one-pot reaction procedure. The chiral compounds can be transformed by nucleophilic reactions into chiral building blocks useful for the synthesis of natural biologically active products, such as antibiotics and pheromones.