222533-31-5

Basic information

• Product Name: methanesulfonic acid 5-(acetylamino-methyl)-2-methoxy-phenyl ester
• Synonyms: methanesulfonic acid 5-(acetylamino-methyl)-2-methoxy-phenyl ester
• CAS NO: 222533-31-5
• Molecular Weight: 273.31
• Mol File: 222533-31-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methanesulfonic acid 5-(acetylamino-methyl)-2-methoxy-phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: methanesulfonic acid 5-(acetylamino-methyl)-2-methoxy-phenyl ester(222533-31-5)
• EPA Substance Registry System: methanesulfonic acid 5-(acetylamino-methyl)-2-methoxy-phenyl ester(222533-31-5)

Safety Data

• Hazardous Substances Data: 222533-31-5(Hazardous Substances Data)

Upstream product

• 60-35-5 acetamide 
• 50-00-0 formaldehyd 
• 98910-57-7 2-methoxyphenyl mesylate 

Downstream Products

• 42365-68-4 (3-hydroxy-4-methoxyphenyl)methanamine hydrochloride 
• 222533-34-8 N-(3-hydroxy-4-methoxy-benzyl)-acetamide 
• 65609-25-8 N-acetyl-3,4-dimethoxybenzylamine 

Relevant articles and documents

Mesyl guaiacol: A versatile intermediate for the synthesis of 5-aminomethyl guaiacol and related compounds

An original synthetic pathway for the preparation of 5-substituted guaiacol derivatives is described. This method relies on the deactivation of the phenol group by converting it into the corresponding mesyl ester. Amidomethylation reactions lead to regioselective C-C bond formation at the 5-position of guaiacol. Thus, 5-aminomethyl-guaiacol was obtained in four steps and 75% overall yield.