222727-06-2

Basic information

• Product Name: S-Ethyl (2R,3S)-3-benzoylamino-2-hydroxy-3-phenylpropanethioate
• Synonyms: S-Ethyl (2R,3S)-3-benzoylamino-2-hydroxy-3-phenylpropanethioate
• CAS NO: 222727-06-2
• Molecular Weight: 329.42
• Mol File: 222727-06-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: S-Ethyl (2R,3S)-3-benzoylamino-2-hydroxy-3-phenylpropanethioate(CAS DataBase Reference)
• NIST Chemistry Reference: S-Ethyl (2R,3S)-3-benzoylamino-2-hydroxy-3-phenylpropanethioate(222727-06-2)
• EPA Substance Registry System: S-Ethyl (2R,3S)-3-benzoylamino-2-hydroxy-3-phenylpropanethioate(222727-06-2)

Safety Data

• Hazardous Substances Data: 222727-06-2(Hazardous Substances Data)

Upstream product

• 202390-82-7 5-Ethyl (2R,3S)-3-amino-2-benzyloxy-3-phenylpropanethioate 
• 129320-33-8 5-Ethyl (2R,3R)-2-benzyloxy-3-hydroxy-3-phenylpropanethioate 
• 202390-83-8 5-Ethyl (2R,3S)-3-benzoylamino-2-benzyloxy-3-phenylpropanethioate 

Downstream Products

• 33069-62-4 taxol 
• 157826-10-3 (2R,4S,5R)-3-benzoyl-2-(4-methoxyphenyl)-4-phenyl-1,3-oxazolidine-5-carboxylic acid 
• 202390-85-0 Methyl (2S,4S,5R)-3-benzoyl-2-(p-methoxyphenyl)-4-phenyl-1,3-oxazolidine-5-carboxylate 
• 157826-09-0 Methyl (2R,4S,5R)-3-benzoyl-2-(p-methoxyphenyl)-4-phenyl-1,3-oxazolidine-5-carboxylate 
• 153652-70-1 (4S,5R)-3-Benzoyl-2,2-dimethyl-4-phenyl-1,3-oxazolidine-5-carboxylic acid 
• 202390-84-9 Methyl (4S,5R)-3-benzoyl-2,2-dimethyl-4-phenyl-1,3-oxazolidine-5-carboxylate 
• 202390-88-3 2',3'-O,N-[(S)-(p-Methoxybenzylidene)]-7-O-(triethylsilyl)paclitaxel 
• 202390-86-1 (2S,4S,5R)-3-Benzoyl-2-(p-methoxyphenyl)-4-phenyl-1,3-oxazolidine-5-carboxylic acid 
• 32981-85-4 methyl (2R,3S)-3-benzoylamino-2-hydroxy-3-phenylpropanoate 

Relevant articles and documents

Total asymmetric synthesis of taxol by dehydration condensation between 7-TES baccatin III and protected N-benzoylphenylisoserines prepared by enantioselective aldol reaction

Total asymmetric synthesis of Taxol was completed by dehydration condensation between a protected N-benzoylphenylisoserine 4 or 9 and 7-TES baccatin in which was prepared from 8-membered ring enone. Taxol side chains 4, 7, 9 and 11, optically active protected N-benzoylphenylisoserines, were successfully synthesized by enantioselective aldol reaction from two achiral starting materials, benzaldehyde and an enol silyl ether derived from S-ethyl benzyloxyethanethioate.