2232-12-4 Usage
Description
1,3-DIIODO-5,5-DIMETHYLHYDANTOIN, also known as DIH, is a white powder chemical compound that serves as a highly efficient and economical reagent for various iodination processes. It is widely utilized in the synthesis of different chemical compounds due to its chemoselective and stereospecific properties.
Uses
Used in Pharmaceutical Industry:
1,3-DIIODO-5,5-DIMETHYLHYDANTOIN is used as a reagent for the preparation of nitriles from corresponding alcohols and amines via oxidative conversion. This application is essential in the synthesis of various pharmaceutical compounds, making it a valuable component in drug development.
Used in Chemical Synthesis:
1,3-DIIODO-5,5-DIMETHYLHYDANTOIN is used as a reagent for the chemoselective, stereospecific iododesilylation of silylated alkenes. This process is crucial in the synthesis of complex organic molecules, which are vital in various chemical and pharmaceutical applications.
Used in Organic Chemistry:
1,3-DIIODO-5,5-DIMETHYLHYDANTOIN is used as a reagent for the preparation of N-benzyl toluenesulfonamides via sulfonylamidation of alkylbenzenes with toluenesulfonamide in the presence of diiododimethylhydantoin. This application is significant in the synthesis of various organic compounds, contributing to the advancement of organic chemistry.
Used in Iodination Reactions:
1,3-DIIODO-5,5-DIMETHYLHYDANTOIN is used as a reagent in iodination reactions, which are essential in the synthesis of various chemical compounds and materials. Its efficiency and cost-effectiveness make it a preferred choice for iodination processes in different industries, including pharmaceuticals, agrochemicals, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 2232-12-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,2,3 and 2 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 2232-12:
(6*2)+(5*2)+(4*3)+(3*2)+(2*1)+(1*2)=44
44 % 10 = 4
So 2232-12-4 is a valid CAS Registry Number.
InChI:InChI=1/C5H6I2N2O2/c1-5(2)3(10)8(6)4(11)9(5)7/h1-2H3
2232-12-4Relevant articles and documents
Preparation method of 2-bromo-5-iodobenzyl alcohol
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Paragraph 0092; 0093, (2018/05/16)
The invention discloses a preparation method of 2-bromo-5-iodobenzyl alcohol. A synthesis route is simple and typical, and is simple and convenient to operate, the yield of target products is high, 1,3-diiodo-5,5-dimethyl hydantoin as an iodization reagen
PRODUCTION METHOD FOR HALOHYDRANTOIN COMPOUND AND HALOHYDRANTOIN COMPOUND
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Paragraph 0054; 0055; 0056; 0057; 0058; 0059; 0060-0066, (2015/11/24)
A method for producing a halohydantoin compound according to the present invention includes the steps of: (a) providing, in a dryer, a composition containing (i) at least one component selected from the group consisting of water, an organic solvent, and elemental halogen and (ii) a halohydantoin compound; and (b) drying the composition under reduced pressure in the dryer, the reduced pressure being reduced to a pressure lower than atmospheric pressure while introducing an inert gas from an outside source into the dryer.
Carbon-14 labeling of a trifluoromethoxy group: Synthesis of a substance P antagonist
Raab, Conrad E.,Dean, Dennis C.,Melillo, David G.
, p. 815 - 829 (2007/10/03)
Synthesis of a carbon-14 labeled trifluoromethoxy group has been accomplished using the stepwise oxidative fluorination-desulfurization of a readily prepared [14C]xanthate (5). This novel labeling procedure allowed a rapid synthesis of substanc