225233-78-3

Basic information

• Product Name: 4-Chloro-DL-hoMophenylalanine
• Synonyms: 4-Chloro-DL-hoMophenylalanine
• CAS NO: 225233-78-3
• Molecular Weight: 213.664
• Mol File: 225233-78-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4-Chloro-DL-hoMophenylalanine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Chloro-DL-hoMophenylalanine(225233-78-3)
• EPA Substance Registry System: 4-Chloro-DL-hoMophenylalanine(225233-78-3)

Safety Data

• Hazardous Substances Data: 225233-78-3(Hazardous Substances Data)

Usage

General Description

4-Chloro-DL-hoMophenylalanine is a chemical compound that is a derivative of the amino acid phenylalanine. It is a white crystalline powder that is used in the pharmaceutical industry as a building block for the synthesis of various drugs and pharmaceuticals. 4-Chloro-DL-hoMophenylalanine is known for its ability to inhibit the activity of certain enzymes and has been studied for its potential applications in the treatment of various medical conditions, including cancer and neurological disorders. It is also used as a research tool in biochemistry and molecular biology to study the effects of amino acid modifications on protein structure and function. However, it is important to handle and use this compound with caution, as it may pose health risks if not properly handled and managed.

Upstream product

• 143-33-9 sodium cyanide 
• 75677-02-0 3-(4-chlorophenyl)propionaldehyde 
• 773837-37-9 sodium cyanide 
• 90877-70-6 ethyl 2-acetamido-2-cyanoacetate 
• 7116-36-1 ethyl 3-(4-chlorophenyl)propanoate 
• 24393-52-0 ethyl (E)-3-(4-chlorophenyl)prop-2-enoate 
• 6282-88-8 3-(p-chlorophenyl)propanol 

Downstream Products

• 917247-90-6 rac-2-hydroxy-4-(4-chlorophenyl)butanoic acid 
• 111-85-3 n-chlorooctane 
• 131403-00-4 2-Amino-4-(4-chloro-phenyl)-butyric acid octyl ester; hydrochloride 

Relevant articles and documents

NEW TRPA1 ANTAGONISTS

The present invention relates to compounds of Formula (I), to the process for preparing such compounds and to their use in the treatment of a pathological condition or disease susceptible to amelioration by TRPA1 channel inhibition or antagonism.

Biocatalytic racemization of (hetero)aryl-aliphatic α- hydroxycarboxylic acids by Lactobacillus spp. proceeds via an oxidation-reduction sequence

The biocatalytic racemization of a range of (hetero)aryl- and (di)aryl-aliphatic α-hydroxycarboxylic acids has been achieved by using whole resting cells of Lactobacillus spp. The essentially mild (physiological) reaction conditions ensure the suppression of undesired side reactions, such as elimination, decomposition or condensation. Cofactor/inhibitor studies using a cell-free extract of Lactobacillus paracasei DSM 20207 reveal that the addition of redox cofactors (NAD+/NADH) leads to a distinct increase in the racemization rate, while strong inhibition is observed in the presence of Thio-NAD+, which suggests that the racemization proceeds by an oxidation-reduction sequence rather than involvement of a "racemase" enzyme. Wiley-VCH Verlag GmbH & Co. KGaA, 2006.