917247-90-6Relevant articles and documents
Synthesis of α-hydroxy carboxylic acids via a nickel(II)- Catalyzed hydrogen transfer process
Tang, Guo,Cheng, Chien-Hong
supporting information; experimental part, p. 1918 - 1922 (2011/10/12)
A new catalytic system for β-alkylation of lactic acid with primary alcohols has been developed. In the presence of nickel(II) acetate tetrahydrate [Ni(OAc)2(H2O)4] and base, lactic acid reacts with primary alcohols to afford the corresponding coupled α-hydroxy carboxylic acids in good to excellent yields via a hydrogen transfer process without any hydrogen acceptor or hydrogen donor. Copyright