225517-81-7 Usage
General Description
(S)-4-N-CBZ-PIPERAZINE-2-CARBOXYLIC ACID METHYL ESTER is a chemical compound that is commonly used in the pharmaceutical industry. It is a methyl ester derivative of piperazine-2-carboxylic acid, and it is typically synthesized by reacting piperazine-2-carboxylic acid with methanol in the presence of a catalyst. (S)-4-N-CBZ-PIPERAZINE-2-CARBOXYLIC ACID METHYL ESTER is often utilized as a precursor or intermediate in the synthesis of various pharmaceutical drugs, especially those that target central nervous system disorders and related conditions. It is important to handle and store (S)-4-N-CBZ-PIPERAZINE-2-CARBOXYLIC ACID METHYL ESTER with care, as it can be hazardous if not handled properly.
Check Digit Verification of cas no
The CAS Registry Mumber 225517-81-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,5,5,1 and 7 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 225517-81:
(8*2)+(7*2)+(6*5)+(5*5)+(4*1)+(3*7)+(2*8)+(1*1)=127
127 % 10 = 7
So 225517-81-7 is a valid CAS Registry Number.
InChI:InChI=1/C14H18N2O4/c1-19-13(17)12-9-16(8-7-15-12)14(18)20-10-11-5-3-2-4-6-11/h2-6,12,15H,7-10H2,1H3/t12-/m0/s1
225517-81-7Relevant articles and documents
KINETIC RESOLUTION OF CHIRAL AMINES
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Page/Page column 69; 70; 71; 78; 79; 80, (2013/03/26)
The present invention refers to a method for the kinetic resolution of a chiral primary or secondary amine by treating the amine with a chiral, hydroxamic acid derived reagent of the formula (I). These chiral reagents are particularly useful for the kinetic resolution of cyclic amines and may be generated in situ in the presence of an N-heterocyclic carbene, thus allowing for a catalytic reaction.