227178-09-8

Basic information

• Product Name: 1-(3-(pyridin-2-yl)phenyl)ethan-1-one
• Synonyms: 1-(3-(pyridin-2-yl)phenyl)ethan-1-one
• CAS NO: 227178-09-8
• Molecular Weight: 197.236
• Mol File: 227178-09-8.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: 1-(3-(pyridin-2-yl)phenyl)ethan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-(pyridin-2-yl)phenyl)ethan-1-one(227178-09-8)
• EPA Substance Registry System: 1-(3-(pyridin-2-yl)phenyl)ethan-1-one(227178-09-8)

Safety Data

• Hazardous Substances Data: 227178-09-8(Hazardous Substances Data)

Usage

Description

1-(3-(pyridin-2-yl)phenyl)ethan-1-one is a ketone compound characterized by a molecular formula of C14H11NO. It features a benzene ring connected to a pyridine ring, with a ketone functional group attached to the ethyl chain. This chemical structure endows it with unique properties that make it a versatile building block for the synthesis of more complex organic molecules. Its potential applications span across various industries, including pharmaceuticals and chemical synthesis, where it can also serve as a reagent in chemical reactions.

Uses

Used in Pharmaceutical Industry:
1-(3-(pyridin-2-yl)phenyl)ethan-1-one is used as an intermediate compound for the development of new pharmaceuticals. Its unique structure allows for the creation of complex organic molecules with potential therapeutic properties, contributing to the advancement of drug discovery and design.
Used in Chemical Synthesis:
In the field of chemical synthesis, 1-(3-(pyridin-2-yl)phenyl)ethan-1-one is used as a valuable building block. Its structure facilitates the synthesis of more complex organic molecules, which can be utilized in various applications, such as the development of new materials, dyes, and other specialty chemicals.
Used as a Reagent in Chemical Reactions:
Due to its unique chemical properties, 1-(3-(pyridin-2-yl)phenyl)ethan-1-one can be employed as a reagent in various chemical reactions. This application allows for the modification and functionalization of other molecules, further expanding the range of potential uses and products that can be derived from this versatile compound.

Upstream product

• 109-04-6 2-bromo-pyridine 
• 17997-47-6 2-tri-n-butylstannylpyridine 
• 2142-63-4 1-(3-Bromophenyl)ethanone 
• 14452-30-3 3'-iodoacetophenone 
• 13737-04-7 2-(trimethylsilyl)pyridine 
• 98-98-6 2-Picolinic acid 
• 65007-00-3 pyridin-2-yl trifluoromethanesulfonate 
• 1219454-89-3 2-((difluoromethyl)sulfonyl)pyridine 

Downstream Products

• 1373350-16-3 C₃₇H₃₈N₂O 
• 1355042-73-7 2-(4-(3,5-di-tert-butylphenyl)-6-(3-(pyridin-2-yl)phenyl)pyridin-2-yl)phenol 
• 1355042-85-1 [Pt(2-(4-(3,5-di-tert-butylphenyl)-6-(3-(pyridin-2-yl)phenyl)pyridin-2-yl)phenolate)] 
• 1397290-28-6 4-acetyl-2-(pyridin-2-yl)benzonitrile 
• 1421030-10-5 1-(5-bromo-2,4-difluorophenyl)ethanone 
• 1355042-81-7 1-(5-bromo-2,4-difluorophenyl)ethanone 
• 1373350-01-6 1-(5-bromo-2,4-difluorophenyl)ethanone 
• 1379667-26-1 N-[4-acetyl-2-(pyridin-2-yl)phenyl]-4-methylbenzenesulfonamide 
• 1334336-35-4 1-phenyl-1-(3-(pyridin-2-yl)phenyl)ethanol 
• 1236046-64-2 C₂₀H₁₅NO₂ 
• 1093649-18-3 1-{2-oxo-2-[30-(200-pyridinyl)phenyl]ethyl}pyridinium iodide 

Relevant articles and documents

Access to Branched Allylarenes via Rhodium(III)-Catalyzed C-H Allylation of (Hetero)arenes with 2-Methylidenetrimethylene Carbonate

A rhodium(III)-catalyzed C-H allylation of (hetero)arenes by using 2-methylidenetrimethylene carbonate as an efficient allylic source has been developed for the first time. Five different directing groups including oxime, N-nitroso, purine, pyridine, and pyrimidine were compatible, delivering various branched allylarenes bearing an allylic hydroxyl group in moderate to excellent yields.

Nickel-Catalyzed Reductive 2-Pyridination of Aryl Iodides with Difluoromethyl 2-Pyridyl Sulfone

A novel nickel-catalyzed reductive cross-coupling between aryl iodides and difluoromethyl 2-pyridyl sulfone (2-PySO2CF2H) enables C(sp2)-C(sp2) bond formation through selective C(sp2)-S bond cleavage, which demonstrates the new reactivity of 2-PySO2CF2H reagent. This method employs readily available nickel catalyst and sulfones as cross-electrophile coupling partners, providing facile access to biaryls under mild reaction conditions without pregeneration of arylmetal reagents.

Mild, Selective Ru-Catalyzed Deuteration Using D2O as a Deuterium Source

A method for the selective deuteration of polyfunctional organic molecules using catalytic amounts of [RuCl2(PPh3)3] and D2O as a deuterium source is presented. Through variation of additives like CuI, KOH, and various amounts of zinc powder, orthogonal chemoselectivities in the deuteration process are observed. Mechanistic investigation indicates the presence of different, defined Ru-complexes under the given specific conditions.