227751-47-5Relevant articles and documents
Pyrrolidine integrin regulator and application thereof
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Paragraph 0228; 0236-0238, (2021/09/08)
Disclosed are a compound as represented by formula I, and a racemate, a stereoisomer, a tautomer, an isotopic marker, a nitrogen oxide, a solvate, a polymorph, a metabolite, an ester, and a prodrug thereof or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising same, a preparation method therefor, and the medical use thereof. The structure of formula I is as follows:
INHIBITORS OF (ALPHA-V)(BETA-6) INTEGRIN
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Page/Page column 54; 55, (2018/09/21)
Disclosed are small molecule inhibitors of ανβ6 integrin, and methods of using them to treat a number of specific diseases or conditions.
N-ACYL AMINO ACID COMPOUNDS AND METHODS OF USE
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Paragraph 0348, (2018/03/28)
The invention relates to compounds of formula (I), or a salt thereof wherein R1, A, L, and R2 and n are as described herein. Compounds of formula (I) and pharmaceutical compositions thereof are ανβ1 integrin inhibitors that are useful for treating tissue specific fibrosis.
