228243-48-9Relevant articles and documents
An industrial process for synthesizing lodenosine (FddA)
Izawa, Kunisuke,Takamatsu, Satoshi,Katayama, Satoshi,Hirose, Naoko,Kozai, Shigetaka,Maruyama, Tokumi
, p. 507 - 517 (2003)
Two industrial synthetic approaches to Lodenosine (1, FddA, 9-(2,3-dideoxy-2-fluoro-β-D-threo-pentofuranosyl) adenine) via a purine riboside or a purine 3′-deoxyriboside are described. Several novel applications of deoxygenation and fluorination methods are compared considering reaction yields, economy, safety and environmental concerns.
Introduction of a benzoyl group onto riboside in aqueous solution: One- step synthesis of 6-chloropurine 2',3'-di-O-benzoylriboside
Kozai, Shigetada,Takamatsu, Satoshi,Izawa, Kunisuke,Maruyama, Tokumi
, p. 4355 - 4358 (2007/10/03)
A benzoyl group was introduced onto the 3'-hydroxyl group of 6- chloropurine riboside by treatment with benzoylating agents in the presence of an organic or inorganic base in aqueous solution, in which further reaction gave 6-chloropurine 2',3'-di-O-benzo