35638-82-5Relevant articles and documents
A new method for the synthesis of 2′-O-benzyladenosine using mitsunobu reaction
Kozai, Shigetada,Fuzikawa, Tomoyo,Harumoto, Keisuke,Maruyama, Tokumi
, p. 145 - 151 (2003)
A new method to introduce a benzyl group onto the 2′-OH of purine ribonucleoside is described. Thus, 6-chloropurine 3′-O-benzoylriboside and its 5′-O-trityl congener were condensed with benzyl alcohol using the Mitsunobu reaction to give the 2′-O-benzyl derivative. The yields were varied from 4.6 to 62.9% depending on the solvent used. The product was converted to adenosine, indicating that the stereochemistry at C-2′ is retained.
Introduction of a benzyl group onto the 2′-OH of 6-chloropurine 3′-O-benzoylriboside
Kozai, Shigetada,Fuzikawa, Tomoyo,Harumoto, Keisuke,Maruyama, Tokumi
, p. 779 - 781 (2007/10/03)
A new method to introduce a benzyl group onto the 2′-OH of purine ribonucleoside is described. Thus, 6-chloropurine 3′-O-benzoylriboside and its 5′-O-trityl congener were condensed with benzyl alcohol using the Mitsunobu reaction to give the 2′-O-benzyl derivative. The yields were varied from 4.6 to 62.9% depending on the solvent. The product was converted to adenosine, indicating that the stereochemistry at C-2′ is retained.
Nucleosides. VI. Synthesis of 2'-O-, 3'-O- and 5'-O-benzyladenosine
Myles,Pfeiderer
, p. 3327 - 3333 (2007/10/04)
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