22928-91-2

Basic information

• Product Name: ethyl 5-methyl-1H-1,2-diazepine-1-carboxylate
• Synonyms: ethyl 5-methyl-1H-1,2-diazepine-1-carboxylate
• CAS NO: 22928-91-2
• Molecular Weight: 180.206
• Mol File: 22928-91-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: ethyl 5-methyl-1H-1,2-diazepine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 5-methyl-1H-1,2-diazepine-1-carboxylate(22928-91-2)
• EPA Substance Registry System: ethyl 5-methyl-1H-1,2-diazepine-1-carboxylate(22928-91-2)

Safety Data

• Hazardous Substances Data: 22928-91-2(Hazardous Substances Data)

Upstream product

• 22928-85-4 4-Methyl-1-ethoxycarbonyliminopyridiniumylid 

Downstream Products

• 64762-43-2 8-methyl-3-phenyl-9aH-[1,2,4]oxadiazolo[4,5-b][1,2]diazepine-5-carboxylic acid ethyl ester 
• 64762-44-3 7a-methyl-3,10-diphenyl-(7ar,10ac,10bc)-10a,10b-dihydro-7aH-isoxazolo[4,5-d][1,2,4]oxadiazolo[4,5-b][1,2]diazepine-5-carboxylic acid ethyl ester 
• 64762-39-6 8-methyl-3-(2,4,6-trimethyl-phenyl)-9aH-[1,2,4]oxadiazolo[4,5-b][1,2]diazepine-5-carboxylic acid ethyl ester 
• 61767-17-7 <7α,8α>-5-Methyl-9-oxo-8-phthalimido-1,2-diazabicyclo<5.2.0>nona-3,5-dien-2-carbonsaeure-ethylester 
• 20116-65-8 dimethyl 4-methylphthalate 
• 115125-42-3 1-ethoxycarbonyl-3,4-bismethoxycarbonylpyrazole 
• 121670-79-9 1-ethoxycarbonyl-6-methyl-3,3a-bismethoxycarbonyl-3a,7a-dihydroindazole 
• 144584-49-6 N'-[(Z)-3-[3-(2,4,6-Trimethyl-phenyl)-isoxazol-4-yl]-but-2-en-(E)-ylidene]-hydrazinecarboxylic acid ethyl ester 
• 144584-48-5 6b-Methyl-3-(2,4,6-trimethyl-phenyl)-3a,3b,6a,6b-tetrahydro-1-oxa-2,4,5-triaza-cyclobutadicyclopentene-4-carboxylic acid ethyl ester 
• 87958-08-5 <7α,8α>-8-(4-Chlorphenylsulfonyloxy)-5-methyl-9-oxo-1,2-diazabicyclo<5.2.0>nona-3,5-dien-2-carbonsaeure-ethylester 
• 77134-02-2 5-Methyl-9-oxo-1,2-diazabicyclo<5.2.0>nona-3,5-dien-5-carbonsaeure-ethylester 
• 77134-03-3 <7α,8α>-5,8-Dimethyl-9-oxo-1,2-diazabicyclo<5.2.0>nona-3,5-dien-2-carbonsaeure-ethylester 
• 144584-55-4 N'-[(Z)-3-[3-(4-Bromo-2,6-dimethyl-phenyl)-isoxazol-4-yl]-but-2-en-(E)-ylidene]-hydrazinecarboxylic acid ethyl ester 
• 144584-54-3 3-(4-Bromo-2,6-dimethyl-phenyl)-6b-methyl-3a,3b,6a,6b-tetrahydro-1-oxa-2,4,5-triaza-cyclobutadicyclopentene-4-carboxylic acid ethyl ester 

Relevant articles and documents

Stereospecific Synthesis of 2-Oxazinyl-4-oxoazetidinecarbamates Starting from a 1,2-Diazephine. A New Type of Intramolecular Transbenzoylation

Azetidinodiazepines 4b and 4c react with acylnitroso dienophiles 5a-c, specifically from their convexe α-side, but in a non-regiospecific way, leading thereby stereospecifically to the expected adducts 6a-d and 7a-d.The three-dimensional structures of 6a and 7a were determined by X-ray analyses which corroborated their NMR data.OsO4 cis-glycolization occured in good yield with the inverse adducts 7a and 7e and led to the rearranged products 10.These latter ones result from an intramolecular N- to O-transbenzoylation of the short-lived intermediates 9 followed by fragmentation of the aminal function.X-Ray analysis of 7a showed the N(10) atom to be pyramidal, a result which demonstrates that it does not have any pronounced benzamide character; otherwise no such N- to O-transbenzoylation would have taken place.Structure and relative configuration of 10a were ascertained by X-ray analysis which confirmed its NMR data as well as the stereochemical outcome of its formation.

Studies on diazepines. XVI. Synthesis of monocyclic 1,3-diazepines. (1). Thermolysis of 1,2-diazepines formed from methylpyridine N-imides

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