22943-99-3

Basic information

• Product Name: [2-(hydroxymethyl)-4,5-dimethoxy-phenyl]methanol
• Synonyms: [2-(hydroxymethyl)-4,5-dimethoxy-phenyl]methanol
• CAS NO: 22943-99-3
• Molecular Formula: C₁₀H₁₄O₄
• Molecular Weight: 0
• Mol File: 22943-99-3.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 361.9°Cat760mmHg
• Flash Point: 172.7°C
• Appearance: /
• Density: 1.2g/cm³
• Vapor Pressure: 7.17E-06mmHg at 25°C
• Refractive Index: 1.549
• CAS DataBase Reference: [2-(hydroxymethyl)-4,5-dimethoxy-phenyl]methanol(CAS DataBase Reference)
• NIST Chemistry Reference: [2-(hydroxymethyl)-4,5-dimethoxy-phenyl]methanol(22943-99-3)
• EPA Substance Registry System: [2-(hydroxymethyl)-4,5-dimethoxy-phenyl]methanol(22943-99-3)

Safety Data

• Hazardous Substances Data: 22943-99-3(Hazardous Substances Data)

Usage

Description

[2-(hydroxymethyl)-4,5-dimethoxy-phenyl]methanol, also known as syringaresinol, is a natural compound derived from the guaiacyl subunit of lignin. It is found in various plants, such as flaxseed, sesame seeds, avocado, and olive. Syringaresinol has been studied for its potential health benefits, including antioxidant and anti-inflammatory properties, as well as its potential use in the treatment of cancer, diabetes, and cardiovascular diseases. It also has anti-aging effects, making it a promising compound for cosmetic and skincare product development.

Uses

Used in Pharmaceutical Applications:
Syringaresinol is used as a therapeutic agent for various health conditions due to its antioxidant, anti-inflammatory, and potential disease-treating properties. It is being investigated for its use in the treatment of cancer, diabetes, and cardiovascular diseases.
Used in Cosmetic and Skincare Applications:
Syringaresinol is used as an active ingredient in the development of cosmetic and skincare products, leveraging its anti-aging effects to improve skin health and appearance.
Used in Antioxidant Applications:
Syringaresinol is used as a natural antioxidant in the food and beverage industry, as well as in the pharmaceutical and cosmetic industries, to protect products from oxidative damage and extend their shelf life.
Used in Functional Food and Nutraceutical Applications:
Syringaresinol is used as a functional ingredient in the development of food and nutraceutical products, providing health benefits beyond basic nutrition, such as antioxidant and anti-inflammatory effects.
Used in Research and Development:
Syringaresinol is used as a compound of interest in scientific research, particularly in the fields of medicine, pharmacology, and wellness, to explore its potential applications and mechanisms of action in various health conditions and product development.

InChI:InChI=1/C10H14O4/c1-13-9-3-7(5-11)8(6-12)4-10(9)14-2/h3-4,11-12H,5-6H2,1-2H3

Upstream product

• 531-88-4 5,6-dimethoxyphthalide 
• 75833-55-5 4,5-bisacetoxymethylveratrole 
• 93-07-2 Veratric acid 
• 91-16-7 1,2-dimethoxybenzene 
• 1134-52-7 1,2-Dimethoxy-4,5-bis(chloromethyl)benzene 
• 4821-94-7 4,5-dimethoxyphthalic anhydride 

Downstream Products

• 43073-12-7 4,5-dimethoxy-phthalaldehyde 
• 26726-81-8 1,2-bis(bromomethyl)-4,5-dimethoxybenzene 
• 77619-89-7 3-hydroxy-5,6-dimethoxyisobenzofuran-1(3H)-one 
• 24006-88-0 1,2-Bis(cyanomethyl)-4,5-dimethoxybenzol 
• 30117-80-7 1.2-Bis-(carbaethoxymethyl)-4.5-dimethoxybenzol 
• 26758-01-0 1,2-Dimethoxy-4,5-bis-aethoxymethyl-benzol 
• 26758-09-8 6,7-dimethoxy-3-(3,4,5-trimethoxy-benzoyl)-3,4-dihydro-1H-benzo[d][1,2]oxazine 
• 43073-13-8 1,2-bis(dibromomethyl)4,5-dimethoxybenzene 
• 75833-57-7 1,2-bisiodomethyl-4,5-dimethoxybenzene 

Relevant articles and documents

A Unified Catalytic Asymmetric (4+1) and (5+1) Annulation Strategy to Access Chiral Spirooxindole-Fused Oxacycles

A unified catalytic asymmetric (N+1) (N=4, 5) annulation reaction of oxindoles with bifunctional peroxides has been achieved in the presence of a chiral phase-transfer catalyst (PTC). This general strategy utilizes peroxides as unique bielectrophilic four- or five-atom synthons to participate in the C?C and the subsequent umpolung C?O bond-forming reactions with one-carbon unit nucleophiles, thus providing a distinct method to access the valuable chiral spirooxindole-tetrahydrofurans and -tetrahydropyrans with good yields and high enantioselectivities under mild conditions. DFT calculations were performed to rationalize the origin of high enantioselectivity. The gram-scale syntheses and synthetic utility of the resultant products were also demonstrated.

NOVEL BICYCLIC-COMPOUNDS FOR USE AS A MEDICAMENT, IN PARTICULAR FOR TREATMENT OF PARKINSON'S DISEASE

The invention relates to novel small molecule compounds having a basic structure as depicted by formula (A), where in particular exemplary embodiments R1 is -OH, R2 is -NO2 and R3 is H, R4 and R5

Exploring O-stannyl ketyl and acyl radical cyclizations for the synthesis of γ-lactone-fused benzopyrans and benzofurans

The synthesis of a series of γ-lactone-fused benzopyrans and benzofurans, analogues of the pyranonaphthoquinone antibiotics, is reported. Preparation of the heterocycles was achieved by either O-stannyl ketyl or acyl radical cyclization of benzaldehyde pr