23152-99-0

Basic information

• Product Name: 4'-ISOPROPYLPHENYL ACETYLENE
• Synonyms: 4-(1-methylethyl)phenylethyne;benzene,1-ethynyl-4-(1-methylethyl)-;cumene,p-ethynyl-;p-ethynylcumene;1-ETHYNYL-4-ISOPROPYL-BENZENE;1-ETHYNYL-4-(1-METHYLETHYL)-BENZENE;4'-ISOPROPYLPHENYL ACETYLENE;Benzene, 1-ethynyl-4-(1-methylethyl)- (9CI)
• CAS NO: 23152-99-0
• Molecular Formula: C₁₁H₁₂
• Molecular Weight: 144.21
• Mol File: 23152-99-0.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 193.8 °C at 760 mmHg
• Flash Point: 60.3 °C
• Appearance: /
• Density: 0.91 g/cm³
• Vapor Pressure: 0.637mmHg at 25°C
• Refractive Index: 1.518
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4'-ISOPROPYLPHENYL ACETYLENE(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-ISOPROPYLPHENYL ACETYLENE(23152-99-0)
• EPA Substance Registry System: 4'-ISOPROPYLPHENYL ACETYLENE(23152-99-0)

Safety Data

• Statements: 36/37/38-43
• Safety Statements: 26-36/37/39-36/37
• Hazardous Substances Data: 23152-99-0(Hazardous Substances Data)

Usage

General Description

4'-Isopropylphenyl acetylene is a chemical compound with the molecular formula C12H14. It is a colorless liquid with a molecular weight of 158.24 g/mol. 4'-ISOPROPYLPHENYL ACETYLENE is mainly used in research and development and manufacturing of pharmaceuticals, dyes, and other organic compounds. Its properties include a boiling point of 246°C and a flash point of 67°C. 4'-Isopropylphenyl acetylene is considered to be potentially harmful if swallowed and may cause skin and eye irritation upon contact. It is important to handle this chemical with care and use appropriate safety measures when working with it.

InChI:InChI=1/C11H12/c1-4-10-5-7-11(8-6-10)9(2)3/h1,5-9H,2-3H3

Upstream product

• 142521-08-2 1,1-dibromo-2-(4-isopropylphenyl)ethene 
• 384850-37-7 1-(4-isopropylphenyl)-2-trimethylsilylacetylene 
• 17356-09-1 4-iodocumene 
• 122-03-2 (4-isopropylbenzaldehyde) 
• 3368-21-6 (E)-4-isopropylcinnamic acid 
• 21047-57-4 diethyl (1-diazo-2-oxopropyl)phosphonate 
• 586-61-8 4-iso-propylbromobenzene 
• 558-13-4 carbon tetrabromide 

Downstream Products

• 75599-92-7 3,4-Difluoro-6-(p-isopropylphenyl)-2H-pyran-2-one 
• 75599-95-0 1-Phenyl-3,3,4-trifluoro-1-cyclobutene-4-carboxylic Acid 
• 99255-60-4 [2-(3,4-Dimethoxy-phenyl)-ethyl]-{2-[2-(4-isopropyl-phenylethynyl)-5-methoxy-phenyl]-1-methyl-ethyl}-methyl-amine 
• 35672-49-2 1,4-Di-p-isopropylphenylbuta-1,3-diin 
• 325793-45-1 2-(4-isopropyl-phenylethynyl)-benzothiazole 
• 79135-52-7 1,2-bis(4-isopropylphenyl)acetylene 
• 109619-13-8 (Z)-1-(2-Hydroxy-phenyl)-3-(4-isopropyl-phenyl)-3-phenylamino-propenone 
• 92831-11-3 2-[4-(1-methylethyl)phenyl]-4H-1-benzopyran-4-one 
• 1392492-90-8 diethyl 5-(4-isopropylphenyl)-1H-pyrazol-3-ylphosphonate 
• 1401560-07-3 2-((4-isopropylphenyl)ethynyl)-N,N-dimethylaniline 
• 1459714-34-1 5-(4-isopropylphenyl)-3-methylenepent-4-yn-1-ol 

Relevant articles and documents

Piers′ Borane-Induced Tetramerization of Arylacetylenes

We herein report that the reaction of Piers′ borane, i. e. HB(C6F5)2, with an excess of arylacetylenes at room temperature leads to tetramerization of the acetylene and the diastereoselective formation of boryl-substituted

Calcium carbide catalytically activated with tetra-: N -butyl ammonium fluoride for Sonogashira cross coupling reactions

We report a novel method for the direct synthesis of mono- and bis-arylated alkynes utilizing catalytically activated CaC2 as the alkyne component. This fluoride-activated cross coupling reaction provides advantages over existing methods regarding operational simplicity, use of readily available starting materials, and low cost.

One-pot, two-step conversion of aldehydes to phosphonyl- and sulfonylpyrazoles using Bestmann-Ohira reagent

A one-pot, two-step, three-component method for the conversion of commercially available aldehydes to phosphonylpyrazoles has been developed, demonstrating, for the first time, the dual reactivity of the Bestmann-Ohira reagent (BOR) in a single-pot transformation. This method, extended to the synthesis of sulfonylpyrazoles by employing BOR in the first step and a diazomethyl sulfone in the second step, is complementary, with regard to regioselectivity, to the previous methods for the synthesis of such functionalized pyrazoles.