23229-72-3

Basic information

• Product Name: 5-ETHYL-THIOPHENE-2-CARBOXYLIC ACID
• Synonyms: RARECHEM AL BE 0391;AKOS MSC-0715;AKOS B000094;5-ETHYL-2-THIOPHENECARBOXYLIC ACID;5-ETHYL-THIOPHENE-2-CARBOXYLIC ACID;ASINEX-REAG BAS 10238292;ART-CHEM-BB B000094;CHEMBRDG-BB 4402392
• CAS NO: 23229-72-3
• Molecular Formula: C₇H₈O₂S
• Molecular Weight: 156.2
• Mol File: 23229-72-3.mol
• Article Data: 7

Chemical Properties

• Melting Point: 69 °C
• Boiling Point: 286.1 °C at 760 mmHg
• Flash Point: 126.8 °C
• Appearance: /
• Density: 1.257 g/cm³
• Vapor Pressure: 0.00126mmHg at 25°C
• Refractive Index: 1.575
• Storage Temp.: 2-8°C
• PKA: 3.69±0.10(Predicted)
• CAS DataBase Reference: 5-ETHYL-THIOPHENE-2-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 5-ETHYL-THIOPHENE-2-CARBOXYLIC ACID(23229-72-3)
• EPA Substance Registry System: 5-ETHYL-THIOPHENE-2-CARBOXYLIC ACID(23229-72-3)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 23229-72-3(Hazardous Substances Data)

Usage

General Description

5-Ethyl-thiophene-2-carboxylic Acid is an organic compound that falls on the list of classified substances based on hazard information. It can be identified by its CAS number 5392-28-9, which is a unique numerical identifier assigned by the Chemical Abstracts Service. The compound includes elements of carbon, hydrogen, sulphur, and oxygen. It is also included in the subgroup Thiophenes, which consists of sulfur heterocycles. Its physical and chemical properties, toxicity, and reactions under certain conditions may vary, necessitating careful handling and comprehensive knowledge when used in various applications. Its specific use or role in industries or applications may depend on the synthesis and structural configurations.

InChI:InChI=1/C7H8O2S/c1-2-5-3-4-6(10-5)7(8)9/h3-4H,2H2,1H3,(H,8,9)

Upstream product

• 36880-33-8 5-ethyl-thiophene-2-carbaldehyde 
• 62323-44-8 2-bromo-5-ethylthiophene 
• 33252-91-4 5-ethyl-2-iodothiophene 
• 541-41-3 chloroformic acid ethyl ester 
• 4066-41-5 5-acetylthiophene-2-carboxylic acid 
• 18761-46-1 1-(5-ethyl-thiophen-2-yl)-ethanone 
• 527-72-0 2-thiophenylcarboxylic acid 
• 75-03-6 ethyl iodide 
• 59753-16-1 C₅H₂O₂S^(2-)*2Li⁽¹⁺⁾ 
• 872-55-9 2-ethylthiophene 

Downstream Products

• 64964-17-6 5-Ethyl-2-thiophencarbonsaeurechlorid 
• 111-14-8 oenanthic acid 
• 6933-26-2 (5-ethyl-2-thienyl)phenylmethanone 
• 1400704-84-8 (S)-[(5-ethyl-thiophene-2-carbonyl)amino]-2-({2-[3-(3-hydroxy-phenyl)propylamino]-4,6-dimethyl-pyrimidine-5-carbonyl}amino)-3-propionic acid methyl ester 
• 1010113-59-3 3-(3,5-dimethyl-4-oxiranylmethoxy-phenyl)-5-(5-ethyl-thiophen-2-yl)-[1,2,4]oxadiazole 
• 1010113-62-8 1-amino-3-{4-[5-(5-ethyl-thiophen-2-yl)-[1,2,4]oxadiazol-3-yl]-2,6-dimethyl-phenoxy}-propan-2-ol 
• 1010114-08-5 (S)-N-(3-{4-[5-(5-ethyl-thiophen-2-yl)-[1,2,4]oxadiazol-3-yl]-2,6-dimethylphenoxy}-2-hydroxypropyl)-2-hydroxyacetamide 
• 1010113-49-1 4-[5-(5-ethyl-thiophen-2-yl)-[1,2,4]oxadiazol-3-yl]-2,6-dimethyl-phenol 

Relevant articles and documents

Novel S1P1 receptor agonists - Part 2: From bicyclo[3.1.0] hexane-fused thiophenes to isobutyl substituted thiophenes

Previously, we reported on the discovery of a novel series of bicyclo[3.1.0]hexane fused thiophene derivatives that serve as potent and selective S1P1 receptor agonists. Here, we discuss our efforts to simplify the bicyclohexane fused thiophene

NOVEL THIOPHENE DERIVATIVES

The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents.

TETRACYCLIC COMPOUNDS AS DOPAMINE AGONISTS

A tetracyclic compound of the formula: STR1 wherein A and the atoms to which it is attached and the optional double bond represent a mono-or di-heterocyclic ring selected from: STR2 wherein R 1, R. sup.2, R 3, R 4 and X are specifically defined, which compounds are useful in the treatment of dopamine-related neurological, psychological and cardiovascular disorders as well as in the treatment of substance abuse and other addictive behavior disorders, cognitive impairment and attention deficit disorder.