64964-17-6Relevant articles and documents
N-Glycosyl-thiophene-2-carboxamides: Effects on endothelial cell growth in the presence and absence of bFGF - A significant increase in potency using per-O-acetylated sugar analogues
Rawe, Sarah L.,Zaric, Violeta,O'Boyle, Kathy M.,Murphy, Paul V.
, p. 1316 - 1319 (2006)
Inhibitors of endothelial cell proliferation are of interest in development of therapies for angiogenesis related disease. N-Glucosyl-thiophene-2- carboxamides have been synthesized and evaluated for their effects on proliferation in bovine aortic endothelial cells. Per-O-acetylated-N-glucosyl- thiophene-2-carboxamides showed improved inhibition of both serum and bFGF stimulated uptake of [3H]thymidine, when compared to non-acetylated analogues.
Liquid Crystalline Compounds in the Thiophene Series, Part 11. Liquid Crystalline Thiophene Carboxylic Esters
Kossmehl, Gerhard,Hirsch, Barbara
, p. 1265 - 1274 (2007/10/03)
The new series of ten 4,4'-bis(5-alkyl-2-thienylcarbonyloxy)azobenzenes (2a-2j) and ten 2,5-bis(5-alkyl-2-thienylcarbonyloxy)toluenes (3a-3j) were prepared.These, as yet unknown esters were characterized in relation to their structures by elemental analyses, IR, UV, 1H NMR spectra and MS.The azobenzene-esters 2a-2j which form liquid crystalline phases were studied by microscopy under polarized light and DSC (differential scanning calorimetry).Through the observation of the optical textures nematic phases were monitored.Only 2j has an additional smectic phase; 2h and 2i form monotropic smectic phases during cooling.The toluene-esters 3a-3j do not form liquid crystalline phases. - Keywords: Liquid Crystalline Thiophene Derivatives; Thiophene Carboxylic Esters; Mesogenic Groups; Liquid Crystalline Esters; Liquid Crystalline Azobenzene Derivatives