23588-89-8

Basic information

• Product Name: N,N-diethylethanamine dihydrofluoride
• Synonyms: hydrofluoric acid, compd. with N,N-diethylethanamine (2:1); N,N-Diethylethanamine dihydrofluoride
• CAS NO: 23588-89-8
• Molecular Formula: C₆H₁₇F₂N
• Molecular Weight: 141.2027
• Mol File: 23588-89-8.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 90.5°C at 760 mmHg
• Vapor Pressure: 56.1mmHg at 25°C
• CAS DataBase Reference: N,N-diethylethanamine dihydrofluoride(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-diethylethanamine dihydrofluoride(23588-89-8)
• EPA Substance Registry System: N,N-diethylethanamine dihydrofluoride(23588-89-8)

Safety Data

• Hazardous Substances Data: 23588-89-8(Hazardous Substances Data)

Upstream product

• 2062-98-8 perfluoro(2-propoxypropionyl) fluoride 
• 76-37-9 2,2,3,3-tetrafluoropropanol 
• 422-61-7 perfluoropropanoyl fluoride 
• 375-84-8 2,2,3,3,4,4,5,5,6,6,7,7,7-tridecafluoroheptanoyl fluoride 
• 354-34-7 trifluoroacetyl fluoride 
• 355-80-6 2,2,3,3,4,4,5,5-octafluoropentan-1-ol 
• 38078-09-0 diethylamino-sulfur trifluoride 
• 23588-89-8 triethylamine hydrofluoride 
• 73602-61-6 triethylamine tris(hydrogen fluoride) 
• 121-44-8 triethylamine 
• 23588-89-8 triethylammonium dihydrofluoride 
• 75-89-8 2,2,2-trifluoroethanol 
• 421-83-0 trifluoromethane sulfonyl chloride 
• 375-01-9 2,2,3,3,4,4,4-heptafluorobutanol 

Downstream Products

• 23588-89-8 triethylamine hydrofluoride 
• 23588-89-8 triethylammonium dihydrofluoride 
• 409341-03-3 tert-butyl 4-hydroxy-2-oxopyrrolidine-1-carboxylate 
• 144717-69-1 trans-[Pt(H)(F)(PCy₃)2] 
• 869749-35-9 [(PdMe)2(μ-κ2(P,P)Cy2PCH2PCy2)2(μ-F)][FHF] 
• 155145-20-3 (fluorido)(5,10,15,20-tetramesitylporphyrinato)iron(III) 
• 1414381-42-2 5-bromo-2-[(4-bromophenoxy)difluoromethyl]-1,3-difluorobenzene 
• 1414381-46-6 4'-bromo-4-[difluoro-(4-iodophenoxy)methyl]-3,5,2'-trifluorobiphenyl 
• 1388651-17-9 N-((4aS,5S,7aS)-7a-(2,3-difluorophenyl)-5-(fluoromethyl)-4a,5,7,7a-tetrahydro-4H-furo[3,4-d][1,3]thiazin-2-yl)benzamide 
• 1624605-95-3 benzyl 4-(difluoromethyl)piperidine-1-carboxylate 

Relevant articles and documents

Perfluoroalcohols

Perfluorinated primary alcohol adducts with triethylamine were prepared from lower perfluorinated acid fluorides and triethylamine monohydrofluoride. They are stable compounds and may be used as a source of RFO groups in organic syntheses.

Synthesis of trifluoromethyl ethers and difluoro(methylthio)methyl ethers by the reaction of dithiocarbonates with IF5-pyridine-HF

Trifluoromethyl ether and difluoro(methylthio)methyl ether of phenols and aliphatic alcohols were selectively synthesized from the corresponding dithiocarbonates. When IF5-pyridine-HF was used alone in the reaction of the dithiocarbonate, the difluoro(methylthio)methyl ether was selectively formed. On the other hand, by the additional use of Et3N-6HF with IF5-pyridine-HF, trifluoromethyl ether was formed selectively. Various functional groups such as ester, ether, amide, and acetonide could tolerate the reaction conditions, and various functionalized difluoro(methylthio)methyl ethers and trifluoromethyl ethers were synthesized.

Antisense modulation of CDC14A expression

Antisense compounds, compositions and methods are provided for modulating the expression of CDC14A. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding CDC14A. Methods of using these compounds for modulation of CDC14A expression and for treatment of diseases associated with expression of CDC14A are provided.