23645-04-7

Basic information

• Product Name: 2-Butanone, 4-aMino-
• Synonyms: 2-Butanone, 4-aMino-;4-amino-2-butanone;4-Aminobutan-2-one
• CAS NO: 23645-04-7
• Molecular Formula: C4H9NO
• Molecular Weight: 87.12036
• EINECS: -0
• Mol File: 23645-04-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 154.7±23.0 °C(Predicted)
• Appearance: /
• Density: 0.913±0.06 g/cm3(Predicted)
• PKA: 8.80±0.10(Predicted)
• CAS DataBase Reference: 2-Butanone, 4-aMino-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Butanone, 4-aMino-(23645-04-7)
• EPA Substance Registry System: 2-Butanone, 4-aMino-(23645-04-7)

Safety Data

• Hazardous Substances Data: 23645-04-7(Hazardous Substances Data)

Usage

General Description

4-amino-2-butanone, also known as piperidin-4-one, is an organic compound with the chemical formula C4H9NO. It is a derivative of butanone and is commonly used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. The compound is a white solid at room temperature and has a faint amine-like odor. It is used in the production of various pharmaceuticals and as a precursor in the synthesis of other organic compounds. 4-amino-2-butanone is also used in the preparation of pesticides and other agricultural chemicals. It is a versatile chemical that has applications in a wide range of industries.

Upstream product

• 660-88-8 5-aminopentanoic acid 
• 78-94-4 methyl vinyl ketone 
• 2524-49-4 3-butene-1-amine 
• 7647-01-0 hydrogenchloride 
• 4657-08-3 3-oxo-5-phthalimido-pentanoic acid ethyl ester 
• 325168-22-7 4-azido-2-methyl-1-butene 
• 114963-62-1 4-amino-butan-2-ol 

Downstream Products

• 54614-95-8 (3-Oxo-butyl)-carbamic acid tert-butyl ester 

Relevant articles and documents

Cyclopropanediamines. 6. Autocatalytic Conversion of 1-Methyl-r-1,t-2-cyclopropanediamine into 4-Aminobutan-2-one in Aqueous Buffer Solutions of pH 6.5-10. Azomethine Ylides as Intermediates in the Catalysis by Alkyl Ketones

The pKa values of 1,2-cyclopropanediammonium dibromides (1-5*2HBr) were determined by potentiometric titration with KOH.Corrections for overlapping ionizations and for the varying ionic strength were employed in the calculation of the thermodynamic acidities.The equilibrium constant KE = 2.9 of the two monoprotonated forms of trans-3b*H+ was derived from the pKa values and the pH dependence of proton spectra which were interpreted with the help of nuclear Overhauser experiments.The autocatalytic conversion of trans-3a*2HBr into 4-aminobutan-2-one (8) in various buffer solutions of pH = 6.5-10 was monitored by proton spectroscopy.This sequence of reactions is subject to a general acid/base catalysis and also catalyzed by acetone and butanone.

NEW CLASS OF GAMMA DELTA T CELLS ACTIVATORS AND USE THEREOF

The present invention relates to a new class of compounds having γδ T cells activating properties, a composition comprising these compounds and methods for regulating an immune response in a subject comprising the step of administering these compounds.

Palladium-Catalyzed Oxidation of Amino Alkenes to Cyclic Imines or Enamines and Amino Ketones

Amino alkenes of the type CH2=CH(CH2)nNH2 (n = 3,4) are cyclized to pyrrolines or piperideines under ''Wacker process''conditions.Amino alkenes with a secondary amino group yield the corresponding cyclic enamines, while tertiary amino alkenes give amino ketones.