23662-66-0Relevant articles and documents
A supporting france for cloth as the starting material of the preparation method (by machine translation)
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Paragraph 0007; 0023; 0029, (2017/12/06)
The invention discloses a method for supporting france for cloth starting material N - ((3 R, 4 R) - 4 - methyl - 1 - benzyl - 3 - piperidinyl) - N - methyl - 7 - paratoluene sulfonyl - 7 H - pyrrolo [2, 3 - D] pyrimidine - 4 - amine (I) synthetic method, specific steps are as follows: to 4 - methyl pyridine as the starting material, with the benzyl chloride undergo nucleophilic substitution by the 4 - methyl - 1 - phenylmethyl - pyridine hydrochloride, under the action of the sodium borohydride reduction reaction, borohydrite - oxidation reaction, hydroxy oxidation, the introduction of the reductive amination of the stereo selectivity of the two chiral center, through a readily available and inexpensive chiral acid (L - DTTA) splitting, to obtain optically pure intermediates (3 R, 4 R) - (1 - benzyl - 4 - methyl - piperidin - 3 - yl) - methylamine, and finally with the 4 - chloro pyrrolo pyrimidine condensation is obtained. The whole method raw materials are easy, simple operation, after treatment is easy, and the cost is low. (by machine translation)
Zwitterionic chromophores and macromolecules containing such chromophores
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, (2008/06/13)
The invention disclosed relates to functionalized zwitterionic chromophores of structural formula III and III′. Wherein A is a linear or branched alkyl group having up to 20 carbon atoms and the desired functional groups, B is hydrogen, alkyl, aryl, halo, heterocyclic, alkoxy or nitro groups at 2, 3, 5 or 6 positions on the pyridine ring, C is hydrogen, aryl or a linear or branched alkyl group at 2′, 3′, 5′ or 6′ positions on the benzene ring, which has up to 70 carbon atoms and contains the desired functional group, D is a linear or branched alkyl, aryl or substituted aryl group, which has up to 70 carbon atoms and contains the desired functional group, R is C1-C4 alkyl or aryl, and m is an integer of from 0 to 4.
Pyrrolo[2,3-d]pyrimidine compounds
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, (2008/06/13)
A compound of the formula wherein R1, R2 and R3 are as defined above, useful as inhibitors of protein kinases, such as the enzyme Janus Kinase 3.