23724-60-9 Usage
Description
ACETAMIDE-2,2,2-D3, also known as deuterated acetamide, is a compound derived from acetamide with deuterium atoms replacing three hydrogen atoms. This isotopic substitution allows for unique properties and applications in various fields, particularly in spectroscopy and vibrational studies.
Uses
Used in Infrared Spectral Studies:
ACETAMIDE-2,2,2-D3 is used as a reference compound for infrared spectral studies, providing valuable information on the normal vibrations of acetamide and its deuterated analogs. The deuterium substitution alters the vibrational frequencies, making it easier to analyze and differentiate between various molecular structures.
Used in Normal Vibrations Analysis:
In the field of molecular vibrations, ACETAMIDE-2,2,2-D3 serves as a useful tool for analyzing the normal vibrations of acetamide and its deuterated analogs. The presence of deuterium atoms in the compound leads to distinct vibrational patterns, which can be utilized to study the molecular dynamics and interactions of these compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 23724-60-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,7,2 and 4 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 23724-60:
(7*2)+(6*3)+(5*7)+(4*2)+(3*4)+(2*6)+(1*0)=99
99 % 10 = 9
So 23724-60-9 is a valid CAS Registry Number.
23724-60-9Relevant articles and documents
A low temperature matrix isolation infrared study of acetamides. I. Acetamide and some deuterated derivatives
Knudsen, R.,Sala, O.,Hase, Y.
, p. 187 - 196 (1994)
The IR spectra of acetamide and some of its deuterated derivatives in argon matrices (14 K) have been obtained in the region 4000-200 cm-1.An injection system was developed to avoid multiple site splitting.A normal coordinate analysis has been carried out for the a" vibrational modes and from the C NH2 torsional force constant the potential barrier was calculated to be 81 kJ mol-1.
DEUTERATED FEZOLINETANT
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Paragraph 0105; 0108, (2019/01/29)
The present invention relates to deuterated fezolinetant (R)-(4-fluorophenyl)-(8-methyl-3-(3-(methyl-d3)-1,2,4-thiadiazol-5-yl)-5,6-dihydro-[1,2,4]trizolo[4,3-a]pyrazin-7(8H)-yl)methanone, or a pharmaceutically acceptable solvate thereof, as NK-3 antagoni
Transamidation of primary amides with amines catalyzed by zirconocene dichloride
Atkinson, Benjamin N.,Chhatwal, A. Rosie,Lomax, Helen V.,Walton, James W.,Williams, Jonathan M. J.
supporting information, p. 11626 - 11628 (2013/01/15)
Zirconocene dichloride (Cp2ZrCl2) has been shown to be an effective catalyst for the transamidation of primary amides with amines in cyclohexane at 80°C in 5-24 hours. For favourable substrates, the reaction can be performed at temperatures as low as 30°C.