23740-98-9Relevant articles and documents
Synthesis of 3-substituted 3H-indol-3-ols by the reaction of 2-isocyanophenyl ketones with Grignard reagents
Kobayashi, Kazuhiro,Okamura, Yuta,Fukamachi, Shuhei,Konishi, Hisatoshi
experimental part, p. 7961 - 7964 (2010/10/19)
A facile method for the synthesis of 3-substituted 3H-indol-3-ols has been developed. Thus, 2-isocyanophenyl ketones are allowed to react with various Grignard reagents to give the corresponding desired indolol derivatives in generally fair to good yields. The formation of 3-aryl-2,3-dimethylindolin-3-ols by the reaction of 2-isocyanobenzophenones with 2 M amounts of methylmagnesium bromide is also reported.
Heterocyclic 8?-Systems, 16 - Elimination Reactions of 2-Alkoxy-3-hydroxyindolines
Beitzke, Bernhard,Schmidt, Richard R.
, p. 1726 - 1731 (2007/10/02)
Thermolysis of 2-ethoxy-3-hydroxyindolines 1a - f affords oxindoles 3a - f as main products and the corresponding 3-indolinones 2a - f as by-products.The reaction course via indole 2,3-oxide intermediates is discussed.For this reason rearrangement reactio