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241479-75-4

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241479-75-4 Usage

Description

(αR,βR)-β-(2,5-Difluorophenyl)-β-hydroxy-α-Methyl-1H-1,2,4-triazole-1-butanaMide is a chiral compound characterized by its specific stereochemistry, with both the α and β carbons being in the R configuration. It is a key intermediate in the pharmaceutical industry due to its role in the synthesis of antifungal agents.

Uses

Used in Pharmaceutical Industry:
(αR,βR)-β-(2,5-Difluorophenyl)-β-hydroxy-α-Methyl-1H-1,2,4-triazole-1-butanaMide is used as an intermediate in the synthesis of Isavuconazole (I777830), a triazole-based antifungal agent. It is specifically utilized for the treatment of invasive fungal infections, providing a targeted approach to combat these infections and improve patient outcomes.
Isavuconazole is a broad-spectrum antifungal medication that works by inhibiting the synthesis of fungal cell membranes, thereby disrupting the growth and proliferation of the fungi. The compound (αR,βR)-β-(2,5-Difluorophenyl)-β-hydroxy-α-Methyl-1H-1,2,4-triazole-1-butanaMide plays a crucial role in the development of this medication, contributing to its effectiveness and potential in treating various fungal infections.

Check Digit Verification of cas no

The CAS Registry Mumber 241479-75-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,4,1,4,7 and 9 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 241479-75:
(8*2)+(7*4)+(6*1)+(5*4)+(4*7)+(3*9)+(2*7)+(1*5)=144
144 % 10 = 4
So 241479-75-4 is a valid CAS Registry Number.

241479-75-4Relevant articles and documents

AN IMPROVED PROCESS FOR THE PREPARATION OF TRIAZOLE DERIVATIVES

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, (2021/12/31)

The present invention relates to an improved process for the preparation of triazole derivatives such as ravuconazole and isavuconazole.

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