241499-35-4

Basic information

• Product Name: 1-(3-Methyl-butyl)-piperazine-2-carboxylic acid methyl ester
• Synonyms: 1-(3-Methyl-butyl)-piperazine-2-carboxylic acid methyl ester
• CAS NO: 241499-35-4
• Molecular Weight: 214.308
• Mol File: 241499-35-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(3-Methyl-butyl)-piperazine-2-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-Methyl-butyl)-piperazine-2-carboxylic acid methyl ester(241499-35-4)
• EPA Substance Registry System: 1-(3-Methyl-butyl)-piperazine-2-carboxylic acid methyl ester(241499-35-4)

Safety Data

• Hazardous Substances Data: 241499-35-4(Hazardous Substances Data)

Upstream product

• 2758-98-7 2-methoxycarbonyltetrahydropyrazine 

Relevant articles and documents

Synthesis and biological evaluation of substituted 4-(OBz)phenylalanine derivatives as novel N-type calcium channel blockers

Selective N-type Voltage Activated Calcium Channel (VACC) blockers have shown utility in several models of stroke and pain. In the process of searching for small molecules as N-type calcium channel blockers, we have identified a series of N,N-dialkylpeptidylamines (e.g., PD 175069) with potent functional activity at N-type VACC. Further modification of the leucine moiety of PD 175069 with a cyclized ring structure provides a series of novel molecules. Syntheses and pharmacological evaluation of the series are presented.