2419-94-5 Usage
Description
Boc-L-Glutamic acid, also known as N-Boc-protected L-Glutamic acid, is a derivative of the nonessential amino acid L-Glutamic acid. It plays a crucial role in the mammalian central nervous system and serves as a neurotransmitter for cone photoreceptors in the human brain. Boc-L-Glutamic acid is characterized by its white to off-white crystalline powder appearance.
Uses
Used in Pharmaceutical Industry:
Boc-L-Glutamic acid is used as an active pharmaceutical ingredient for the treatment of patients with liver disease accompanied by encephalopathy, also known as 'hepatic coma.' Its role in the central nervous system makes it a valuable compound in addressing this specific medical condition.
Used in Neurotransmission:
Boc-L-Glutamic acid is used as a neurotransmitter for cone photoreceptors in the human brain, playing a significant role in the proper functioning of the nervous system and maintaining overall brain health.
Used in Research and Development:
Due to its unique properties and applications, Boc-L-Glutamic acid is also utilized in research and development for the discovery of new pharmaceutical compounds and therapies targeting the central nervous system and related conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 2419-94-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,4,1 and 9 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 2419-94:
(6*2)+(5*4)+(4*1)+(3*9)+(2*9)+(1*4)=85
85 % 10 = 5
So 2419-94-5 is a valid CAS Registry Number.
InChI:InChI=1/C10H17NO6/c1-10(2,3)17-9(16)11-6(8(14)15)4-5-7(12)13/h6H,4-5H2,1-3H3,(H,11,16)(H,12,13)(H,14,15)/t6-/m1/s1
2419-94-5Relevant articles and documents
Enzymatic removal of carboxyl protecting groups. 2. Cleavage of the benzyl and methyl moieties
Barbayianni, Efrosini,Fotakopoulou, Irene,Schmidt, Marlen,Constantinou-Kokotou, Violetta,Bornscheuer, Uwe T.,Kokotos, George
, p. 8730 - 8733 (2007/10/03)
Enzymes are versatile reagents for the efficient removal of methyl and benzyl protecting groups. An esterase from Bacillus subtilis (BS2) and a lipase from Candida antarctica (CAL-A) allow a mild and selective removal of these moieties in high yields without affecting other functional groups.
PROPERTIES OF Nα,Nca-DI-TERT-BUTYLOXYCARBONYL-ω-CARBAMOYL-α-AMINO ACIDS AND DIRECT SYNTHESIS OF PROTECTED HOMOGLUTAMIC ACID DERIVATIVES
Sakura, Naoki,Hirose, Kyoko,Hashimoto, Tadashi
, p. 3506 - 3509 (2007/10/02)
The protected carboxamide function of Nα,Nca-di-tert-butyloxy-carbonyl-ω-carbamoyl-α-amino acids worked well with nucleophilic reagents.Applying this novel reactivity, we developed an efficient synthetic route to Nα-tert-butyloxycarbonylhomoglutamic acid and its derivatives, including Nα-tert-butyloxycarbonylhomoglutamic acid δ-benzyl ester, from Nα,Nca-di-tert-butyloxycarbonylhomoglutamine.KEYWORDS - protected homoglutamic acid synthesis; Nca-tert-butyloxycarbonylated carboxamide; hydrolysis; selective deprotection; Nα-tert-butyloxycarbonylhomoglutamic acid δ-benzyl ester; Nα-tert-butyloxycarbonylhomoglutamic acid α-tert-butyl ester; Nα-tert-butyloxycarbonylhomoglutamine; optical purity