24247-53-8Relevant articles and documents
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Shostakovskii,M.F. et al.
, (1963)
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Studies towards total synthesis of antillatoxin: Investigation of the indium-mediated allylation reactions of carbonyl compounds with β-bromocrotylbromide in water
Loh, Teck-Peng,Cao, Guo-Qiang,Pei, Jian
, p. 1453 - 1456 (1998)
Indium mediates the coupling of β-bromocrotylbromide with carbonyl compounds in saturated ammonium chloride in the presence of lanthanide triflate under sonication to give the corresponding compounds in good yield and moderate to high syn diastereoselecti
Catalytic Enantioselective [2+2] Cycloaddition of α-Halo Acroleins: Construction of Cyclobutanes Containing Two Tetrasubstituted Stereocenters
Cheng, Guolin,Gao, Lizhu,Rao, Weidong,Xu, Jingjing,Yan, Zhongliang,Zeng, Lei,Zhang, Dongsheng
supporting information, p. 21890 - 21894 (2020/10/02)
A catalytic enantioselective formal [2+2] cycloaddition between α-halo acroleins and electronically diverse arylalkenes is described. In the presence of (S)-oxazaborolidinium cation as the catalyst, densely functionalized cyclobutanes containing two vicin
Reactions of α-haloacroleins with azides: Highly regioselective synthesis of formyl triazoles
Zhang, Dongsheng,Fan, Yingzhu,Yan, Zhongliang,Nie, Yi,Xiong, Xingquan,Gao, Lizhu
supporting information, p. 4211 - 4216 (2019/08/07)
A general metal-free route to 1,4-disubstituted and 1,4,5-trisubstituted 1,2,3-triazoles was developed. α-Haloacroleins reacted with organic azides in a DMSO/H2O mixture solvent at room temperature to produce 1,4-disubstituted triazoles (up to 99%) with exclusive regioselectivities. This protocol is convenient and scalable with a broad substrate scope including aliphatic and aromatic azides. The resulting triazoles exhibited an aldehyde group at the C4 position and demonstrated synthetic utilizations. One 1,2,3-triazole compound containing diastereotopic protons was also identified.