24275-68-1 Usage
General Description
4-(9-Acridinyl)-N,N-dimethylaniline, also known as acridine orange, is a fluorescent dye commonly used in molecular biology and microscopy applications. It is a cationic dye that can intercalate with DNA and RNA, making it useful for staining and visualization of nucleic acids in cells and tissues. Acridine orange is also used in the field of microbiology for bacterial viability assays, as well as in cell viability assays and cell cycle analysis. Its fluorescent properties make it a valuable tool for the study of cellular processes and can be used in both live and fixed cell imaging. Additionally, acridine orange has been investigated for its potential anti-cancer properties and has shown promise as a therapeutic agent in cancer treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 24275-68-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,4,2,7 and 5 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 24275-68:
(7*2)+(6*4)+(5*2)+(4*7)+(3*5)+(2*6)+(1*8)=111
111 % 10 = 1
So 24275-68-1 is a valid CAS Registry Number.
InChI:InChI=1/C21H18N2/c1-23(2)16-13-11-15(12-14-16)21-17-7-3-5-9-19(17)22-20-10-6-4-8-18(20)21/h3-14H,1-2H3
24275-68-1Relevant articles and documents
Regioselective C-H bond functionalizations of acridines using organozinc reagents
Hyodo, Isao,Tobisu, Mamoru,Chatani, Naoto
supporting information; experimental part, p. 308 - 310 (2012/01/05)
Despite the recent advance in C-H bond functionalization chemistry, the C-H bonds in the acridine ring system, which is an important scaffold in medicinal and material science, have met with limited success, due, in part, to the lack of activated C-H bonds adjacent to the ring nitrogen atom. Herein, several protocols that can effect the regioselective arylation and alkylation of acridines at the C-4 and C-9 positions are described.
