243-55-0Relevant articles and documents
Green Synthesis of Indeno[1,2-b]quinoxalines Using β-Cyclodextrin as Catalyst
Feng, Jun-Feng,Li, Bang-Jing,Liao, Li-Guo,Liu, Fan,Qiu, Zhen-Jiang,Song, Meng-Meng,Tan, Min,Zhang, Sheng
, (2022/01/25)
An efficient, mild, and green method was developed for the synthesis of indeno[1,2b]quinoxaline derivatives via o-phenylenediamine (OPD) and 2-indanone derivatives utilizing βcyclodextrin (β-CD) as the supramolecular catalyst. The reaction can be carried out in water and in a solid state at room temperature. β-CD can also catalyze the reaction of indan-1,2-dione with OPD with a high degree of efficiency. Compared to the reported methods, this procedure is milder, simpler, and less toxic, making it an eco-friendly alternative. In addition, the β-CD can be recovered and reused without the loss of activity.
Mechanochemical solid-state synthesis of 2-aminothiazoles, quinoxalines and benzoylbenzofurans from ketones by one-pot sequential acid- and base-mediated reactions
Nagarajaiah, Honnappa,Mishra, Abhaya Kumar,Moorthy, Jarugu Narasimha
, p. 4129 - 4135 (2016/06/14)
α-Chloroketones-obtained by the atom-economical chlorination of ketones with trichloroisocyanuric acid (TCCA) in the presence of p-TSA under ball-milling conditions-were set up for a sequential base-mediated condensation reaction with thiourea/thiosemicarbazides, o-phenylenediamine and salicylaldehyde to afford 2-aminothiazoles, 2-hydrazinylthiazoles, quinoxalines and benzoylbenzofurans, respectively, in respectable yields. The viability of one-pot sequential acid- and base-mediated reactions in the solid state under ball-milling conditions is thus demonstrated.
Saccharin as an organocatalyst for quinoxalines and pyrido[2,3-b[pyrazines Syntheses
Lassagne, Frederic,Chevallier, Floris,Mongin, Florence
supporting information, p. 141 - 149 (2013/11/06)
A room-temperature procedure using saccharin as catalyst has been described for the cyclocondensation of different 1,2-arylenediamines with various 1,2-dicarbonyl compounds, yielding either quinoxalines or pyrido[2,3-b] pyrazines. The reactions proceed in very short reaction times in methanol, and the target heterocycles are isolated in quantitative yields after addition of water, filtration, and drying. Substituted pyrido[2,3-b]pyrazines can also be reached regioselectively by reacting α-ketoaldehydes with 2,3-diaminopyridine. Taylor and Francis Group, LLC.