245759-61-9 Usage
Description
(1R)-1-[4-(benzyloxy)-3-nitrophenyl]-2-[(2R)-1-(4-methoxyphenyl)propan-2-yl]aminoethanol is a complex organic molecule with a unique structure that features a nitro group, a benzyl ether, an amino group, and a hydroxyl group, among other functional groups. The presence of a chiral center indicates that it can exist as two enantiomers. (1R)-1-[4-(benzyloxy)-3-nitrophenyl]-2-[(2R)-1-(4-methoxyphenyl)propan-2-yl]aminoethanol's structure suggests potential biological or pharmaceutical activities, as the benzyl, nitro, and methoxy groups are commonly found in drugs and natural products with medicinal properties. Due to its intricate composition, this compound is likely to exhibit a wide range of chemical and pharmacological properties.
Uses
Used in Pharmaceutical Industry:
(1R)-1-[4-(benzyloxy)-3-nitrophenyl]-2-[(2R)-1-(4-methoxyphenyl)propan-2-yl]aminoethanol is used as a potential pharmaceutical agent for its possible biological activities. The presence of various functional groups, such as the benzyl, nitro, and methoxy groups, suggests that this compound may have medicinal properties, making it a candidate for drug development and therapeutic applications.
Used in Chemical Research:
In the field of chemical research, (1R)-1-[4-(benzyloxy)-3-nitrophenyl]-2-[(2R)-1-(4-methoxyphenyl)propan-2-yl]aminoethanol serves as a subject of study for understanding its chemical properties and reactivity. (1R)-1-[4-(benzyloxy)-3-nitrophenyl]-2-[(2R)-1-(4-methoxyphenyl)propan-2-yl]aminoethanol's complex structure and the presence of multiple functional groups make it an interesting case for exploring chemical reactions and mechanisms, potentially leading to new insights and applications in synthetic chemistry.
Used in Chiral Chemistry:
(1R)-1-[4-(benzyloxy)-3-nitrophenyl]-2-[(2R)-1-(4-methoxyphenyl)propan-2-yl]aminoethanol, with its chiral center, is utilized in chiral chemistry to investigate the synthesis and separation of enantiomers. The study of enantiomers is crucial in various fields, including pharmaceuticals, where the different spatial arrangements of atoms can lead to distinct biological activities and effects. (1R)-1-[4-(benzyloxy)-3-nitrophenyl]-2-[(2R)-1-(4-methoxyphenyl)propan-2-yl]aminoethanol can be used to develop methods for enantioselective synthesis and to understand the role of stereochemistry in chemical and biological processes.
Check Digit Verification of cas no
The CAS Registry Mumber 245759-61-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,4,5,7,5 and 9 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 245759-61:
(8*2)+(7*4)+(6*5)+(5*7)+(4*5)+(3*9)+(2*6)+(1*1)=169
169 % 10 = 9
So 245759-61-9 is a valid CAS Registry Number.
245759-61-9Relevant articles and documents
An efficient enantioselective synthesis of (R,R)-formoterol, a potent bronchodilator, using lipases
Campos, Francisco,Bosch, M. Pilar,Guerrero, Angel
, p. 2705 - 2717 (2007/10/03)
The potent β2-adrenergic receptor agonist formoterol (R,R)-1 has been obtained in enantiomerically pure form by a convenient chemoenzymatic approach by coupling of epoxide (R)-6 with the unprotected primary amine (R)-9. Both chiral precursors have been prepared by enantiodifferentiation processes involving Pseudomonas cepacia (lipase PS) and Candida antarctica lipase (CALB), respectively. For the resolution of amine 9, we have found that utilization of triethylamine as non-reactive base enhances the reaction rate and the enantioselectivity of the process. The key coupling reaction of (R)-6 and (R)-9 has been conducted through derivatization of the amine with the labile trimethylsilyl group, which liberates the amino group of the resulting amino alcohol (R,R)-11 upon column chromatography purification. In this way, the overall approach is shorter than others previously described. Copyright (C) 2000 Elsevier Science Ltd.
