24619-05-4

Basic information

• Product Name: 5,5'-dithiodisalicylic acid
• Synonyms: 5,5'-dithiodisalicylic acid;3,3'-Dithiobis(6-hydroxybenzoic acid);Einecs 246-360-4
• CAS NO: 24619-05-4
• Molecular Formula: C₁₄H₁₀O₆S₂
• Molecular Weight: 338.3556
• EINECS: 246-360-4
• Mol File: 24619-05-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 603.6 °C at 760 mmHg
• Flash Point: 318.9 °C
• Appearance: /
• Density: 1.75 g/cm³
• CAS DataBase Reference: 5,5'-dithiodisalicylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5,5'-dithiodisalicylic acid(24619-05-4)
• EPA Substance Registry System: 5,5'-dithiodisalicylic acid(24619-05-4)

Safety Data

• Hazardous Substances Data: 24619-05-4(Hazardous Substances Data)

Usage

General Description

5,5'-dithiodisalicylic acid is a chemical compound with the formula C14H10O6S2. It is a derivative of salicylic acid and contains a sulfur-sulfur bond. 5,5'-dithiodisalicylic acid is often used as a chelating agent to bind to metal ions, and it is commonly used in analytical chemistry to measure the concentration of metal ions in solution. Additionally, 5,5'-dithiodisalicylic acid has been studied for its potential antioxidant and anticancer properties. It has also been investigated for its potential use in the development of drug delivery systems. Due to its ability to bind to metal ions and its potential biological activities, this compound has applications in various research and industrial settings.

Upstream product

• 21222-64-0 2-hydroxy-5-thiocyanato-benzoic acid 
• 58765-12-1 2-hydroxy-5-mercaptobenzoic acid 
• 17243-13-9 5-chlorosulfonyl-2-hydroxybenzoic acid 
• 97-05-2 5-sulfosalicylic Acid 
• 69-72-7 salicylic acid 
• 89-57-6 5-Aminosalicylic Acid 

Downstream Products

• 58765-12-1 2-hydroxy-5-mercaptobenzoic acid 

Relevant articles and documents

Ethanol catalyzed synthesis of titanocene aryl carboxylate complexes and crystal structure of (η5-C5H5) 2Ti(2-OH-5-S-O2CC6H3)2

A method for the synthesis of titanocene (IV) aryl carboxylate complexes is presented in this paper. It is based on the fact that alcohol can catalyze the reaction between Cp2TiCl2 and aryl carboxylate ligands in the presence of sodium hydroxide (NaOH). The effects of the catalyst on the reaction system were studied and the possible reaction mechanism was proposed. This method was used to prepare a series of titanocene (IV) aryl carboxylate complexes and a macrocyclic titanocene (5,5′-dithiodisalicylato titanocene), whose structure was determined by X-ray diffraction analysis.

Bacterial reduction as means for colonic drug delivery: Can other chemical groups provide an alternative to the azo bond?

We compared the rate of colonic bacterial reduction of disulfide and nitro bonds to that of an azo counterpart. The disulfide and nitro reduction rates are comparable to that of azo having a similar molecular structure. We further explored QSAR of bacterial reduction of different nitro compounds giving a Hammett correlation with ρ = 0.553, R2 = 0.97. We conclude that disulfide and nitro compounds have an unexploited potential for use in prodrugs and drug delivery systems targeted to the colon.