246506-79-6Relevant articles and documents
Discovery of a novel chimeric ubenimex–gemcitabine with potent oral antitumor activity
Jiang, Yuqi,Hou, Jinning,Li, Xiaoyang,Huang, Yongxue,Wang, Xuejian,Wu, Jingde,Zhang, Jian,Xu, Wenfang,Zhang, Yingjie
, p. 5787 - 5795 (2016)
Herein, a novel mutual prodrug BC-A1 was discovered by integrating ubenimex and gemcitabine into one molecule. Biological characterization revealed that compound BC-A1 could maintain both the anti-CD13 activity of ubenimex and the cytotoxic activity of ge
MULTI-TARGETED UBENIMEX PRODRUG DERIVATIVE AND PREPARATION METHOD AND USE THEREOF
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Paragraph 0065, (2015/12/08)
The present invention relates to the design, synthesis, and biological study of multi-targeted Ubenimex pro-drug derivative. More particularly, provided in the present invention is a compound as shown by general structural formula (I) (wherein the definit
New stereoselective synthesis of the peptidic aminopeptidase inhibitors bestatin, phebestin and probestin
Righi, Giuliana,D'Achille, Claudia,Pescatore, Giovanna,Bonini, Carlo
, p. 6999 - 7002 (2007/10/03)
Peptidic aminopeptidase inhibitors, bestatin, phebestin and probestin have been prepared by stereo- and regiocontrolled reactions from a common α,β-epoxy ester precursor.