24669-56-5

Basic information

• Product Name: Tricyclo[4.3.1.13,8]undecan-4-one
• Synonyms: Tricyclo[4.3.1.13,8]undecan-4-one;tricyclo[4.3.1.1~3,8~]undecan-4-one(SALTDATA: FREE)
• CAS NO: 24669-56-5
• Molecular Formula: C₁₁H₁₆O
• Molecular Weight: 164.246
• Mol File: 24669-56-5.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 262.8°C at 760 mmHg
• Flash Point: 105.4°C
• Appearance: /
• Density: 1.068g/cm³
• Vapor Pressure: 0.0107mmHg at 25°C
• Refractive Index: 1.523
• CAS DataBase Reference: Tricyclo[4.3.1.13,8]undecan-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: Tricyclo[4.3.1.13,8]undecan-4-one(24669-56-5)
• EPA Substance Registry System: Tricyclo[4.3.1.13,8]undecan-4-one(24669-56-5)

Safety Data

• Hazardous Substances Data: 24669-56-5(Hazardous Substances Data)

Usage

General Description

Tricyclo[4.3.1.13,8]undecan-4-one, also known as ketocamphane, is a bicyclic ketone compound. It is a natural product found in certain plant species and is also commonly used as a fragrance ingredient in cosmetic and personal care products. The chemical structure of tricyclo[4.3.1.13,8]undecan-4-one consists of a unique tricyclic ring system with 11 carbon atoms, giving it a rigid and stable configuration. Tricyclo[4.3.1.13,8]undecan-4-one has been studied for its potential biological activities, including antimicrobial and anti-inflammatory properties, and has shown promise as a versatile building block for organic synthesis in medicinal chemistry and materials science. However, further research is needed to fully understand its potential applications and effects.

InChI:InChI=1/C11H16O/c12-11-6-9-2-7-1-8(3-9)5-10(11)4-7/h7-10H,1-6H2

Upstream product

• 186581-53-3 diazomethane 
• 700-58-3 2-Adamantanone 
• 875-72-9 2-methylideneadamantane 
• 55638-01-2 2,4-Dehydro-5-homoadamantanon 
• 25763-45-5 homoadamantan-4-ol 
• 97382-23-5 3,4-dihydroxytricyclo<4.3.1.1^3,8>undecane 
• 174906-23-1 5-trifluoroacetyltricyclo<4.3.1.1^3,8>undecan-4-one 
• 28529-71-7 (1r,3r,5r,7r)‐2‐(aminomethyl)adamantan‐2‐ol 
• 80-11-5 N-nitroso-p-toluenesulfonamide 
• 281-46-9 homoadamantane 

Downstream Products

• 103499-73-6 homoadamantanone <(2,4,6-triisopropylphenyl)sulfonyl>hydrazone 
• 162463-58-3 3-benzoyl-5-hydroxy-5-trifluoromethyl-3,4-diazatetracyclo<7.3.1.1^7,11.0^2,6>tetradeca-2(6)-ene 
• 25763-46-6 4-Homoadamantyl tosylate 
• 1660-05-5 1-(adamantan-1-yl)propan-1-one 
• 1660-04-4 1-acetyladamantane 
• 133189-63-6 3-Phenyltricyclo<4.3.1.1^3,8>undecan-4-one 
• 133189-58-9 3,4-Dihydroxy-4-phenyltricyclo<4.3.1.1^3,8>undecane 
• 133189-62-5 3-(4-Methoxyphenyl)tricyclo<4.3.1.1^3,8>undecan-4-one 
• 133189-65-8 4-Phenyl-4-homoadamanten-3-yl acetate 
• 133189-57-8 3,4-Dihydroxy-4-(4-methoxyphenyl)tricyclo<4.3.1.1^3,8>undecane 
• 133189-64-7 4-(4-Methoxyphenyl)-4-homoadamanten-3-yl acetate 
• 21898-95-3 1-methoxyhomoadamantane 

Relevant articles and documents

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Convenient Synthesis of Ethyl 5-Oxohomoadamantane-4-carboxylate: A Useful Precursor of Polyfunctional Homoadamantanes

A facile and convenient synthesis of ethyl 5-oxohomoadamantane-4-carboxylate is reported, and its chemical properties as a cage analogue of acetoacetic ester are investigated. Various derivatives of homoadamantane were synthesized through the reaction of 5-oxohomoadamantane-4-carboxylate with electrophilic agents, binucleophiles, and hydrazoic acid. Some new unusual products were obtained by the reaction of that β-keto ester with nitric acid and nitrosyl chloride. Cage compounds synthesized could be used as precursors for the diverse condensed heterocyclic compounds with potential viral ion channel abrogating activity that possess conformationally rigid lipophilic moieties.

METHODS OF USE OF ANTIVIRAL COMPOUNDS

The present invention relates, in part, to methods of treatment, prevention, and inhibition of viral disorders. In one aspect, the present invention relates to inhibition of the M2 proton channel of influenza viruses (e.g. influenza A virus) and other similar viroporins (e.g., VP24 of Ebola and Marburg viruses; and NS3 protein of Bluetongue). The present invention further relates, inter alia, to compounds which have been shown to possess antiviral activity, in particular, inhibiting the M2 proton channel of influenza viruses.