25108-58-1

Basic information

• Product Name: Benzene, 1-bromo-3-(1-methylethenyl)-
• Synonyms: α-methyl-(3-bromo)styrene;2-(m-bromophenyl)propene;2-(3-bromophenyl)-1-propene;2-bromo-α-methylstyrene;1-Brom-3-(1-methylethenyl)benzol;3-bromo-α-methylstyrene
• CAS NO: 25108-58-1
• Molecular Formula: C9H9Br
• Molecular Weight: 197.074
• Mol File: 25108-58-1.mol
• Article Data: 24

Chemical Properties

• CAS DataBase Reference: Benzene, 1-bromo-3-(1-methylethenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-bromo-3-(1-methylethenyl)-(25108-58-1)
• EPA Substance Registry System: Benzene, 1-bromo-3-(1-methylethenyl)-(25108-58-1)

Safety Data

• Hazardous Substances Data: 25108-58-1(Hazardous Substances Data)

Upstream product

• 2065-66-9 methyl-triphenylphosphonium iodide 
• 2142-63-4 1-(3-Bromophenyl)ethanone 
• 1779-49-3 Methyltriphenylphosphonium bromide 
• 766-81-4 3-bromophenylacetylene 
• 917-54-4 methyllithium 
• 138857-31-5 1-Brom-3-(1-bromethenyl)benzol 
• 30951-66-7 2-(3-bromophenyl)-2-propanol 
• 618-89-3 methyl 3-bromobenzoate 
• 75-16-1 methylmagnesium bromide 

Downstream Products

• 1194045-08-3 ethyl 4-(3-bromophenyl)-2-hydroxypent-4-enoate 
• 67159-85-7 5-bromo-3,3-dimethyl-2,3-dihydro-1H-inden-1-one 
• 91715-46-7 3-(prop-1-en-2-yl)benzoic acid 
• 1610769-68-0 N-(2-(3-bromophenyl)-2-chloropropyl)-4-methylbenzenesulfonamide 
• 1450884-61-3 (S)-methyl 4-(3-bromophenyl)-2-hydroxy-2-(trifluoromethyl)-pent-4-enoate 
• 1450884-55-5 (S)-ethyl 4-(3-bromophenyl)-2-hydroxy-2-(trifluoromethyl)pent-4-enoate 
• 59452-90-3 2-(3-bromophenyl)propanal 
• 73761-78-1 2-(3-bromophenyl)-2-methyloxirane 
• 1415643-32-1 1-bromo-3-(3-tosylprop-1-en-2-yl)benzene 

Relevant articles and documents

Synthesis of a photocontrollable hydrogen sulfide donor using ketoprofenate photocages

We report the design, synthesis and application of a directly photocontrollable hydrogen sulfide (H2S) donor, which releases H 2S proportionally to the intensity and duration of photoirradiation. Photocontrolled H2S releas

1,3-Difunctionalization of β-alkyl nitroalkenes via combination of Lewis base catalysis and radical oxidation

Upon treatment with a Lewis base catalyst, β-alkyl-substituted nitroalkenes could be readily converted into allylic nitro compounds. Examples of either C-1 or C-3 functionalization methods have been reported through nitro-elimination, giving alkene products. In this work, successful 1,3-difunctionalization was achieved through a synergetic Lewis base catalysis and TBHP radical oxidation, giving vinylic alkoxyamines in good to excellent yields. This work further extended the general synthetic application of β-alkyl nitroalkenes.

Palladium-Catalyzed Markovnikov Hydroaminocarbonylation of 1,1-Disubstituted and 1,1,2-Trisubstituted Alkenes for Formation of Amides with Quaternary Carbon

Hydroaminocarbonylation of alkenes is one of the most promising yet challenging methods for the synthesis of amides. Herein, we reported the development of a novel and effective Pd-catalyzed Markovnikov hydroaminocarbonylation of 1,1-disubstituted or 1,1,2-trisubstituted alkenes with aniline hydrochloride salts to afford amides bearing an α quaternary carbon. The reaction makes use of readily available starting materials, tolerates a wide range of functional groups, and provides a facile and straightforward approach to a diverse array of amides bearing an α quaternary carbon. Mechanistic investigations suggested that the reaction proceeded through a palladium hydride pathway. The hydropalladation and CO insertion are reversible, and the aminolysis is probably the rate-limiting step.