25186-91-8

Basic information

• Product Name: 1-iodo-4-(phenylsulfinyl)benzene
• Synonyms: 1-iodo-4-(phenylsulfinyl)benzene
• CAS NO: 25186-91-8
• Molecular Weight: 328.173
• Mol File: 25186-91-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-iodo-4-(phenylsulfinyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-iodo-4-(phenylsulfinyl)benzene(25186-91-8)
• EPA Substance Registry System: 1-iodo-4-(phenylsulfinyl)benzene(25186-91-8)

Safety Data

• Hazardous Substances Data: 25186-91-8(Hazardous Substances Data)

Upstream product

• 108-98-5 thiophenol 
• 624-38-4 para-diiodobenzene 
• 88519-49-7 (4-iodophenyl)(phenyl)thioether 

Relevant articles and documents

Palladium/PC-Phos-Catalyzed Enantioselective Arylation of General Sulfenate Anions: Scope and Synthetic Applications

Herein we reported an efficient palladium-catalyzed enantioselective arylation of both alkyl and aryl sulfenate anions to deliver various chiral sulfoxides in good yields (up to 98%) with excellent enantioselectivities (up to 99% ee) by the use of our developed chiral O,P-ligands (PC-Phos). PC-Phos are easily prepared in short steps from inexpensive commercially available starting materials. The single-crystal structure of the PC4/PdCl2 showed that a rarely observed 11-membered ring was formed via the O,P-coordination with the palladium(II) center. The salient features of this method include general substrate scope, ease of scale-up, applicable to the late-stage modification of bioactive compounds, and the synthesis of a marketed medicine Sulindac.