88519-49-7

Basic information

• Product Name: Benzene, 1-iodo-4-(phenylthio)-
• Synonyms: 4-iodophenyl phenyl sulfide;4-Jod-diphenylsulfid
• CAS NO: 88519-49-7
• Molecular Formula: C12H9IS
• Molecular Weight: 312.174
• Mol File: 88519-49-7.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Benzene, 1-iodo-4-(phenylthio)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-iodo-4-(phenylthio)-(88519-49-7)
• EPA Substance Registry System: Benzene, 1-iodo-4-(phenylthio)-(88519-49-7)

Safety Data

• Hazardous Substances Data: 88519-49-7(Hazardous Substances Data)

Upstream product

• 139-66-2 diphenyl sulfide 
• 65662-88-6 phenyl(4-bromophenyl)sulfide 
• 589-87-7 1,4-bromoiodobenzene 
• 108-98-5 thiophenol 
• 624-38-4 para-diiodobenzene 
• 591-50-4 iodobenzene 
• 1193-82-4 racemic methyl phenyl sulfoxide 
• 952-97-6 4-nitrophenyl phenyl sulfide 
• 930-69-8 sodium thiophenolate 
• 1514-50-7 4-iodobenzenediazonium tetrafluoroborate 

Downstream Products

• 14774-79-9 1-iodo-4-(phenylsulfonyl)benzene 
• 25186-91-8 1-iodo-4-(phenylsulfinyl)benzene 
• 53451-90-4 phenyl 4-trifluoromethylphenyl sulfide 
• 1333499-74-3 cis-[PdI(2,2'-bipyridine)(C₆H₄SPh-4)] 
• 872264-83-0 (4-iodosyl-phenyl)-phenyl sulfone 

Relevant articles and documents

Catalytic Access to Functionalized Allylic gem-Difluorides via Fluorinative Meyer–Schuster-Like Rearrangement

An unprecedented approach for efficient synthesis of functionalized allylic gem-difluorides via catalytic fluorinative Meyer–Schuster-like rearrangement is disclosed. This transformation proceeded with readily accessible propargylic fluorides, and low-cost B–F reagents and electrophilic reagents by sulfide catalysis. A series of iodinated, brominated, and trifluoromethylthiolated allylic gem-difluorides that were difficult to access by other methods were facilely produced with a wide range of functional groups. Importantly, the obtained iodinated products could be incorporated into different drugs and natural products, and could be expediently converted into many other valuable gem-difluoroalkyl molecules as well. Mechanistic studies revealed that this reaction went through a regioselective fluorination of alkynes followed by a formal 1,3-fluorine migration under the assistance of the B–F reagents to give the desired products.

Copper-catalyzed selective single arylsulfanylation of aryl diiodides with aryl thiols

Selective single arylsulfanylation reactions of aryl diiodides with aryl or hetaryl thiols to give a broad array of iodine-functionalized sulfides were developed. Further elaboration of the iodine-containing products to provide a variety of aryl and hetaryl sulfides through coupling reactions was also demonstrated. Georg Thieme Verlag Stuttgart, New York.

Synthesis of molecular chains: phenylene thioether and sulfoxide oligomers

The application of a general synthetic approach to prepare molecular chains is reported. It is based on a step-by-step method each consisting first in a Pd-catalyzed reaction between ArI and HXAr′Br (Ar=aryl, Ar′=arylene) to give ArXAr′Br followed by a Cu