253688-60-7 Usage
Chemical Properties
Hydroxy Bosentan is White Powder
Uses
Different sources of media describe the Uses of 253688-60-7 differently. You can refer to the following data:
1. Hydroxy Bosentan is a metabolite of Bosentan, a mixed endothelin receptor antagonist which is used as a vasodilator
2. The active metabolite of Bosentan, a mixed endothelin receptor antagonist which is used as a vasodilator.
Check Digit Verification of cas no
The CAS Registry Mumber 253688-60-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,3,6,8 and 8 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 253688-60:
(8*2)+(7*5)+(6*3)+(5*6)+(4*8)+(3*8)+(2*6)+(1*0)=167
167 % 10 = 7
So 253688-60-7 is a valid CAS Registry Number.
253688-60-7Relevant articles and documents
Chemical synthesis method of bosentan metabolite
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, (2021/07/08)
The invention discloses a chemical synthesis method of bosentan metabolite. According to the method disclosed by the invention, the bosentan metabolite is obtained from 2, 2-dimethyl methyl phenylacetate through six-step reaction. The whole preparation method is high in operability, high in preparation efficiency and low in production cost, and industrial mass production can be achieved. The bosentan metabolite prepared by the invention is higher in bioavailability, can directly play a role in resisting hypertension, and is lower in adverse reaction.
