25370-42-7

Basic information

• Product Name: ETHYL 4-(2-NAPHTHYL)-4-OXOBUTYRATE
• Synonyms: ETHYL 4-(2-NAPHTHYL)-4-OXOBUTYRATE;ethyl 4-(2-naphthyl)-4-oxobutanoate
• CAS NO: 25370-42-7
• Molecular Formula: C16H16O3
• Molecular Weight: 256.3
• Mol File: 25370-42-7.mol
• Article Data: 5

Chemical Properties

• Melting Point: 47-48 °C
• Boiling Point: 419.3°C at 760 mmHg
• Flash Point: 186.6°C
• Appearance: /
• Density: 1.141g/cm³
• Vapor Pressure: 3.06E-07mmHg at 25°C
• Refractive Index: 1.577
• CAS DataBase Reference: ETHYL 4-(2-NAPHTHYL)-4-OXOBUTYRATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 4-(2-NAPHTHYL)-4-OXOBUTYRATE(25370-42-7)
• EPA Substance Registry System: ETHYL 4-(2-NAPHTHYL)-4-OXOBUTYRATE(25370-42-7)

Safety Data

• Hazardous Substances Data: 25370-42-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C16H16O3/c1-2-19-16(18)10-9-15(17)14-8-7-12-5-3-4-6-13(12)11-14/h3-8,11H,2,9-10H2,1H3

Upstream product

• 64-17-5 ethanol 
• 1590-22-3 4-(2-naphthyl)-4-oxobutyric acid 
• 201230-82-2 carbon monoxide 
• 27374-25-0 [(1-Ethoxycyclopropyl)oxy]trimethylsilane 
• 3857-83-8 2-naphthyl triflate 
• 623-73-4 diazoacetic acid ethyl ester 
• 850939-78-5 4-(1-naphthalen-2-yl-vinyl)-morpholine 
• 108-30-5 succinic acid anhydride 
• 91-20-3 naphthalene 
• 1220638-77-6 C₁₉H₂₀O₅ 
• 93-09-4 naphthalene-2-carboxylate 
• 62550-65-6 ethyl 2-naphthoylacetate 
• 3007-91-8 ethyl-2-naphthoate 
• 860395-52-4 2-(1-bromo-vinyl)-naphthalene 

Downstream Products

• 24737-91-5 6-(naphthalen-2-yl)pyridazin-3(2H)-one 
• 867130-43-6 3-chloro-6-[2]naphthyl-pyridazine 

Relevant articles and documents

Synthesis of Unsymmetrical 1,4-Dicarbonyl Compounds by Photocatalytic Oxidative Radical Additions

Herein we report a photocatalytic oxidative radical addition reaction for the synthesis of unsymmetrical 1,4-dicarbonyl compounds. This reaction utilizes a desulfurization process to generate electrophilic radicals, which add to α-halogenated alkenes and undergo further oxidation to deliver 1,4-dicarbonyl compounds. This mild and highly efficient method provides a valuable alternative to known strategies.

π-Interactions as a tool for an easy deposition of meso- tetraferrocenylporphyrin on surfaces

A bottom-up approach was employed to prepare novel Self-Assembled Monolayers (SAMs) in which a naphthyl moiety acted as a "π-binder" for unfunctionalised meso-tetraferrocenylporphyrin (H2TFcP). Four naphthalene derivatives with an appropriate functional group were synthesized and SAMs were prepared both on gold and ITO surfaces. Mixed H 2TFcP-naphthalene films were thoroughly characterized using UV-Vis, XPS and electrochemical techniques. In particular, angle-dependent XPS experiments revealed an almost perpendicular orientation of the porphyrin on surfaces, suggesting that an intercalation occurred among naphthalene units. A large amount of porphyrin was deposited on both the surfaces (in the order of 10-10 mol × cm-2), comparable to that afforded by more conventional covalent linkages. However, significant differences in homogeneity between SAMs on gold and ITO resulted in a diverse electrochemical behaviour. The electrochemical activity of the oxidised porphyrin was restored by prolonged exposure of the modified gold electrode (tens of seconds) to a negative potential, whereas no response was detected after the same treatment on ITO. This novel approach provides a general and versatile strategy to bind meso-substituted porphyrins on a pre-formed monolayer without the necessity for further functionalisations.

Synthesis of 1,4-dicarbonyl compounds and 4-keto pimelates by palladium-catalyzed carbonylation of siloxycyclopropanes

Palladium-catalyzed reaction of a siloxycyclopropane with an aryl triflate under carbon monoxide pressure (10-20 atm) in HMPA and that with carbon monoxide in chloroform provides new synthetic routes to 1,4-dicarbonyl compounds and 4-keto pimelates, respectively. The reaction of a siloxycyclopropane with a vinyl triflate, on the other hand, gives an acyloxycyclopropane instead.