254428-28-9

Basic information

• Product Name: 1'-benzylspiro[cyclopropane-1,3'-indolin]-2'-one
• Synonyms: 1'-benzylspiro[cyclopropane-1,3'-indolin]-2'-one
• CAS NO: 254428-28-9
• Molecular Weight: 249.312
• Mol File: 254428-28-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1'-benzylspiro[cyclopropane-1,3'-indolin]-2'-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1'-benzylspiro[cyclopropane-1,3'-indolin]-2'-one(254428-28-9)
• EPA Substance Registry System: 1'-benzylspiro[cyclopropane-1,3'-indolin]-2'-one(254428-28-9)

Safety Data

• Hazardous Substances Data: 254428-28-9(Hazardous Substances Data)

Upstream product

• 7135-32-2 1-benzylindolin-2-one 
• 106-93-4 ethylene dibromide 
• 1217-89-6 1-benzylisatin 
• 91-56-5 indole-2,3-dione 
• 1774-47-6 trimethylsulfoxonium iodide 

Downstream Products

• 22655-31-8 2',3',6',7',8',8'a-hexahydro-1H,5'H-spiro[indole-3,1'-indolizin]-2-one 
• 254428-51-8 1-benzyl-1'-tosylspiro[indoline-3,3'-pyrrolidine]-2,2'-dione 
• 529483-87-2 1-benzyl-1’-methylspiro[indoline-3,3’-pyrrolidin]-2-one 

Relevant articles and documents

Reactivity of spiroanthraceneoxazolidines with cyclopropanes: An approach to the oxindole alkaloid scaffold

The reaction of N-methylspiro[anthracene-oxazolidine] with spiro[cyclopropane-3,3′-indolin]-2-ones in the presence of MgI2 formed the corresponding spiro[pyrrolidine-3,3′-indolin]-2-ones in 42–65% yields. The use of N-benzylspiro[anthracene-oxazolidine] in this reaction led to the formation of a mixture of the corresponding N-methyl- and N-benzylpyrrolidines.

Facile, novel methodology for the synthesis of spiro[pyrrolidin-3,3'- oxindoles]: Catalyzed ring expansion reactions of cyclopropanes by aldimines

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