2552-45-6Relevant articles and documents
HIGHLY ACTIVE STING PROTEIN AGONIST COMPOUND
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Paragraph 0410-0412, (2021/07/17)
The present invention provides compounds of Formula (I) or (II), pharmaceutical compositions thereof, and methods of using compounds of Formula (I) or (II) to prevent and/or treat immune-related disorders.
DENDRITIC COMPOUNDS INCLUDING A CHELATING, FLUOROCHROME OR RECOGNITION AGENT, COMPOSITIONS INCLUDING SAME AND USES THEREOF
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Paragraph 0350; 0351; 0352, (2016/08/29)
The invention relates to dendritic compounds comprising a chelating, fluorochrome or recognition agent of formula (I), to compositions comprising same, and to uses thereof, wherein in said formula (I): T, L1, D, R, L2, V and n are as defined in the description.
Discovery and optimization of antibacterial AccC inhibitors
Cheng, Cliff C.,Shipps Jr., Gerald W.,Yang, Zhiwei,Sun, Binyuan,Kawahata, Noriyuki,Soucy, Kyle A.,Soriano, Aileen,Orth, Peter,Xiao, Li,Mann, Paul,Black, Todd
scheme or table, p. 6507 - 6514 (2010/05/17)
The biotin carboxylase (AccC) is part of the multi-component bacterial acetyl coenzyme-A carboxylase (ACCase) and is essential for pathogen survival. We describe herein the affinity optimization of an initial hit to give 2-(2-chlorobenzylamino)-1-(cyclohe