256345-54-7Relevant articles and documents
Unsymmetrical cyclic ureas as HIV-1 protease inhibitors: Novel biaryl indazoles as P2/P2' substituents
Patel, Mona,Rodgers, James D.,McHugh Jr., Robert J.,Johnson, Barry L.,Cordova, Beverly C.,Klabe, Ronald M.,Bacheler, Lee T.,Erickson-Viitanen, Susan,Soo S, Ko
, p. 3217 - 3220 (2007/10/03)
The preparation of unsymmetrical cyclic ureas bearing novel biaryl indazoles as P2/P2' substituents was undertaken, utilizing a Suzuki coupling reaction as the key step. Compound 6i was equipotent to the lead compound of the series SE063.