256443-86-4

Basic information

• Product Name: 6-methoxy-5-(5-phenyl-pent-1-ynyl)-2H-phthalazin-1-one
• Synonyms: 6-methoxy-5-(5-phenyl-pent-1-ynyl)-2H-phthalazin-1-one
• CAS NO: 256443-86-4
• Molecular Weight: 318.375
• Mol File: 256443-86-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 6-methoxy-5-(5-phenyl-pent-1-ynyl)-2H-phthalazin-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-methoxy-5-(5-phenyl-pent-1-ynyl)-2H-phthalazin-1-one(256443-86-4)
• EPA Substance Registry System: 6-methoxy-5-(5-phenyl-pent-1-ynyl)-2H-phthalazin-1-one(256443-86-4)

Safety Data

• Hazardous Substances Data: 256443-86-4(Hazardous Substances Data)

Upstream product

• 1823-14-9 5-phenyl-1-pentyne 
• 256443-83-1 trifluoro-methanesulfonic acid 6-methoxy-1-oxo-1,2-dihydro-phthalazin-5-yl ester 
• 228869-37-2 3-Benzyloxy-N,N-diethyl-2-formyl-4-methoxy-benzamide 
• 228869-36-1 3-benzyloxy-N,N-diethyl-4-methoxy-benzamide 
• 228869-38-3 3,4-dihydroxy-5-methoxy-3H-isobenzofuran-1-one 
• 228869-39-4 5-hydroxy-6-methoxy-2H-phthalazin-1-one 
• 6346-05-0 3-benzyloxy-4-methoxybenzaldehyde 
• 41222-60-0 3-benzyloxy-4-methoxybenzoyl chloride 
• 58452-00-9 3-benzyloxy-4-methoxybenzoic acid 

Downstream Products

• 256443-15-9 1-(3,5-dichloro-pyridin-4-ylmethyl)-6-methoxy-5-(5-phenyl-pent-1-ynyl)-phthalazine 
• 256443-87-5 1-Chloro-6-methoxy-5-(5-phenyl-pent-1-ynyl)-phthalazine 

Relevant articles and documents

Phthalazine derivatives phosphodiesterase 4 inhibitors

The present invention provides a compound selected from the group including: 1-(3,5-dichloro-pyridin-4-ylmethyl)-6-methoxy-4-phenyl-phthalazine; 4-(3,5-dichloro-pyridin-4-ylmethyl)-7-methoxy-1H-phthalazin-2-carboxylic acid methyl ester; benzyl-{3-{1-(3,5-dichloro-pyridin-4-ylmethyl)-6-methoxy-phthalazin-5-yl}-prop-2-ynyl}-methyl-amine; 1-(3,5-dichloro-pyridin-4-ylmethyl)-6-methoxy-5-(5-morpholin-4-yl-pent-1-ynyl)-phthalazine dihydrochloride; 3-{1-(3,5-dichloro-pyridin-4-ylmethyl)-6-methoxy-phthalazin-5-yl}-prop-2-yn-1-ol; 1-(3,5-dichloro-pyridin-4-ylmethyl)-6-methoxy-4-morpholin-4-yl-phthalazine; 1-(3,5-dichloro-pyridin-4-ylmethyl)-6-methoxy-4-(1,2,4)triazol-1-yl-phthalazine; N→O derivatives thereof; and pharmaceutically acceptable salts thereof. The invention also provides a pharmaceutical composition which includes a therapeutically effective amount of the above compound in admixture with a suitable carrier.