258503-84-3

Basic information

• Product Name: 2-chloro-N-(4-methyl-3-nitrophenyl) pyridine-4-carboxamide
• Synonyms: 2-chloro-N-(4-methyl-3-nitrophenyl) pyridine-4-carboxamide
• CAS NO: 258503-84-3
• Molecular Weight: 291.694
• Mol File: 258503-84-3.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 2-chloro-N-(4-methyl-3-nitrophenyl) pyridine-4-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-N-(4-methyl-3-nitrophenyl) pyridine-4-carboxamide(258503-84-3)
• EPA Substance Registry System: 2-chloro-N-(4-methyl-3-nitrophenyl) pyridine-4-carboxamide(258503-84-3)

Safety Data

• Hazardous Substances Data: 258503-84-3(Hazardous Substances Data)

Upstream product

• 65287-34-5 2-chloropyridine-4-carbonyl chloride 
• 119-32-4 4-Methyl-3-nitroanilin 
• 258503-86-5 N-(3-amino-4-methylphenyl)-2-morpholinopyridine-4-carboxamide 

Downstream Products

• 258503-86-5 N-(3-amino-4-methylphenyl)-2-morpholinopyridine-4-carboxamide 
• 623153-27-5 C₂₇H₃₀N₈O₃ 
• 623155-40-8 C₂₅H₂₅N₇O₄ 
• 258503-85-4 N-(4-methyl-3-nitrophenyl)-2-morpholinopyridine-4-carboxamide 

Relevant articles and documents

PYRIMIDINE DERIVATIVES

The invention concerns pyrimidine derivatives of Formula (I) wherein m is 0-3 and each Ris a group such as hydroxy, halogeno, trifluoromethyl and cyano; Ris hydrogen, halogeno or (1-6C)alkyl; n is 0-2 and each Ris a group such as hydroxy, halogeno, trifluoromethyl and cyano; p is 0-4; and Qis aryl or heteroaryl; or pharmaceutically acceptable salts or in vivo cleavable esters thereof; processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases or medical conditions mediated by cytokines.

Substituted anilino-quinazoline (or quinoline) compounds and use thereof

The invention concerns amide derivatives of Formula (I), wherein: G is N or CH; R1is a group such as hydroxy, halo, trifluoromethyl, C1-6alkyl and C1-6alkoxy; each of R2and R3is hydrogen, halo, C1-6alkyl, C2-6alkenyl or C2-6alkynyl; R4is a group such as hydrogen, hydroxy, C1-6alkyl, C1-6alkoxy and C3-7cycloalkyl, or R4is of the Formula (IC): —K—J, wherein J is aryl, heteroaryl or heterocyclyl and K is a bond or a group such as oxy and imino, R5is a group such as hydrogen, halo and trifluoromethyl: m is 1-3 and q is 0-4; or pharmaceutically acceptable salts or in vivo cleavable esters thereof; processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases or medical conditions mediated by cytokines.

PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE AS INHIBITORS OF CYTOKINE MEDIATED DISEASE

This invention concerns a bicyclic compound of Formula (I), wherein: G is N, CH or C(CN); ring X is a 5- or 6-membered fused heteroaryl ring which contains 1, 2, or 3 heteroatoms selected from oxygen, sulphur and nitrogen; m is 0-2; Ris a group such a