25855-23-6Relevant articles and documents
Transition-metal free N-arylation of cyanamides by diaryliodonium triflates in aqueous media
Li, Jihui,Zheng, Xinyi,Li, Wei,Zhou, Wei,Zhu, Wen,Zhang, Yucang
supporting information, p. 77 - 80 (2016/01/12)
An operationally simple protocol is established for the synthesis of disubstituted cyanamides through the transition-metal free N-arylation of cyanamides by diaryliodonium triflates in aqueous media. Both alkyl and aryl cyanamides are well compatible with the mild reaction conditions. The one-pot synthesis of ureas is also possible through sequential arylation and hydrolysis of cyanamides, diaryliodonium triflates and H2O with good yields.