2642-98-0

Basic information

• Product Name: 6-AMINOCHRYSENE
• Synonyms: ADCA;6-Amc;Chrysenex;Chrysonex;6-CHRYSENAMINE;6-AMINOCHRYSENE;AMINOCHRYSENE;AMINOCHRYSENE, 6-
• CAS NO: 2642-98-0
• Molecular Formula: C₁₈H₁₃N
• Molecular Weight: 243.3
• EINECS: 220-149-7
• Mol File: 2642-98-0.mol
• Article Data: 8

Chemical Properties

• Melting Point: 209-211 °C(lit.)
• Boiling Point: 376.18°C (rough estimate)
• Flash Point: 286.9°C
• Appearance: /
• Density: 0.8933 (rough estimate)
• Vapor Pressure: 3.56E-10mmHg at 25°C
• Refractive Index: 1.4500 (estimate)
• Storage Temp.: 2-8°C
• Solubility: Acetone (Slightly), Chloroform (Slightly), Methanol (Slightly, Heated)
• PKA: 4.32±0.30(Predicted)
• Water Solubility: 155ug/L(24 oC)
• Merck: 13,2275
• CAS DataBase Reference: 6-AMINOCHRYSENE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-AMINOCHRYSENE(2642-98-0)
• EPA Substance Registry System: 6-AMINOCHRYSENE(2642-98-0)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Safety Statements: 45-36/37/39-26
• WGK Germany: 3
• RTECS: GC0500000
• Hazardous Substances Data: 2642-98-0(Hazardous Substances Data)

Usage

Description

6-Aminochrysene is an organic compound characterized by its orange to brown crystalline powder appearance. It is known for its potent inhibitory effects on transferase activity and its potential use in the synthesis of novel anti-cancer agents.

Uses

Used in Pharmaceutical Research:
6-Aminochrysene is used as a potent inhibitor of transferase activity, which plays a significant role in various biological processes. Its inhibitory properties make it a valuable compound for research and development in the pharmaceutical industry.
Used in Cancer Research:
6-Aminochrysene is utilized in the synthesis of diarylthiourea analogs, which are being investigated as novel anti-cancer agents. These analogs have the potential to offer new treatment options for cancer patients, particularly in targeting specific types of tumors.
Used in Toxicology Studies:
6-Aminochrysene is also used in toxicology studies to produce tumors in mice, providing valuable insights into the mechanisms of carcinogenesis and the development of potential therapeutic interventions.

InChI:InChI=1/C18H13N/c19-18-11-17-13-6-2-1-5-12(13)9-10-15(17)14-7-3-4-8-16(14)18/h1-11H,19H2

Upstream product

• 7496-02-8 6-nitrochrysene 
• 10034-85-2 hydrogen iodide 
• 64-19-7 acetic acid 
• 7647-01-0 hydrogenchloride 
• 218-01-9 chrysene 

Downstream Products

• 37515-51-8 6-hydroxychrysene 
• 94255-53-5 6-Isothiocyanato-chrysen 
• 63018-97-3 6-Acetylaminochrysen 
• 7499-34-5 6-N,N-diacetylaminochrysene 
• 196-79-2 Benzonaphtho<1,2-f>chinolin 
• 625457-62-7 4-{4-[2-(bis-ethylsulfanyl-methyl)-pyrrolidine-1-carbonyl]-2-methoxy-5-nitro-phenoxy}-N-chrysen-6-yl-butyramide 
• 625457-63-8 5-{4-[(S)-2-(Bis-ethylsulfanyl-methyl)-pyrrolidine-1-carbonyl]-2-methoxy-5-nitro-phenoxy}-pentanoic acid chrysen-6-ylamide 
• 17686-89-4 6--chrysen 
• 625457-64-9 4-{5-amino-4-[2-(bis-ethylsulfanyl-methyl)-pyrrolidine-1-carbonyl]-2-methoxy-phenoxy}-N-chrysen-6-yl-butyramide 
• 7499-59-4 6-acetoxychrysene 
• 1224702-81-1 4'-O-demethyl-4β-(1''-chrycenylamino)-4-desoxypodophyllotoxin 
• 1224702-75-3 4β-(6''-chrycenylamino)-4-desoxypodophyllotoxin 
• 1394233-09-0 3-(2-methoxyphenyl)propynoic acid benzylchrysen-6-ylamide 
• 1394233-28-3 C₂₈H₁₉NO₂ 

Relevant articles and documents

Chrysene-Based Azahelicene π-Linker of D-π-D-Type Hole-Transporting Materials for Perovskite Solar Cells

Chrysene is a readily available material for exploring new polycyclic aromatic hydrocarbons (PAHs). In this study, two chrysene based azahelicenes, nine-membered BA7 and ten-membered DA6, are constructed by intermolecular oxidative annulation of 6-aminochrysene and intramolecular annulation of N6,N12-bis(1-chloronaphthalen-2-yl)chrysene-6,12-diamine, respectively. The hexylated BA7 and DA6 and their brominated products were undoubtedly characterized by single crystal XRD. Subsequent amination with bis(9-methyl-9H-carbazol-3-yl)amine (BMCA) electron donor afforded D-π-D-type semiconductors BA7-BMCA and DA6-BMCA with beneficial properties to act as hole transport materials for perovskite solar cell. Compared with 19.4 % champion power conversion efficiency (PCE) of BA7-BMCA based device, a higher PCE of 20.2 % for DA6-BMCA counterpart may be attributed to its S-shaped double helicene-like linker with extended π-conjugated system.

Design and synthesis of novel chrysene-linked pyrrolo[2,1-c][1,4]-benzodiazepine hybrids as potential DNA-binding agents

Chrysene-linked pyrrolobenzodiazepine hybrids have been prepared that posses cytotoxicity in some cancer cell lines. They also exhibit promising DNA-binding affinity and this is supported by molecular modeling studies.

Ultrasound-promoted highly efficient reduction of aromatic nitro compounds to the aromatic amines by samarium/ammonium chloride

Ultrasound-promoted, highly efficient reduction of several aromatic nitro compounds to the aromatic amines was achieved by samarium/ammonium chloride mediated reaction. (C) 2000 Elsevier Science Ltd.