265320-48-7Relevant articles and documents
Synthesis and structure-activity relationships of a novel series of tricyclic dihydropyridine-based KATP openers that potently inhibit bladder contractions in vitro
Carroll, William A.,Agrios, Konstantinos A.,Altenbach, Robert J.,Buckner, Steven A.,Chen, Yiyuan,Coghlan, Michael J.,Daza, Anthony V.,Drizin, Irene,Gopalakrishnan, Murali,Henry, Rodger F.,Kort, Michael E.,Kym, Philip R.,Milicic, Ivan,Smith, Jamie C.,Tang, Rui,Turner, Sean C.,Whiteaker, Kristi L.,Zhang, Henry,Sullivan, James P.
, p. 3180 - 3192 (2007/10/03)
Structure-activity relationships were investigated on a novel series of tricyclic dihydropyridine-containing KATP openers. This diverse group of analogues, comprising a variety of heterocyclic rings fused to the dihydropyridine nucleus, was des
Novel radioligands and their use for identifying potassium channel modulators
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, (2008/06/13)
The present invention relates to novel radioligands and test methods using those radioligands in screening compounds.
Pyrano, piperidino, and thiopyrano compounds and methods of use
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, (2008/06/13)
The present invention provides novel compounds of formula I which may be useful in hyperpolarizing cell membranes, opening potassium channels, relaxing smooth muscle cells, and inhibiting bladder contractions.