267408-63-9

Basic information

• Product Name: N-(2'-Bromophenyl)-N-prop-2-enylpropynamide
• Synonyms: N-(2'-Bromophenyl)-N-prop-2-enylpropynamide
• CAS NO: 267408-63-9
• Molecular Weight: 264.121
• Mol File: 267408-63-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(2'-Bromophenyl)-N-prop-2-enylpropynamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2'-Bromophenyl)-N-prop-2-enylpropynamide(267408-63-9)
• EPA Substance Registry System: N-(2'-Bromophenyl)-N-prop-2-enylpropynamide(267408-63-9)

Safety Data

• Hazardous Substances Data: 267408-63-9(Hazardous Substances Data)

Upstream product

• 615-36-1 2-bromoaniline 
• 41029-45-2 allyl triflate 
• 267408-59-3 N-(2'-Bromophenyl)propynamide 

Downstream Products

• 267408-70-8 N-(2'-Bromophenyl)-N-(1,3-dioxolan-2-ylmethyl)-3-tert-butyldimethylsilylpropynamide 
• 267408-65-1 N-(2'-Bromophenyl)-N-prop-2-enyl-3-tert-butyldimethylsilylpropynamide 

Relevant articles and documents

The synthesis of 3-methyleneindol-2(3H)-ones related to mitomycins via 5-exo-dig aryl radical cyclisation

The synthesis of acetylenic amides from 2-bromoaniline and propiolic acids followed by their cyclisation via the derived aryl radical is presented. Silylation of the terminal end of the triple bond is shown to be required for successful cyclisation to 3-methyleneindol-2(3H)-ones. The exocyclic double bond can be epoxidised using m-chloroperoxybenzoic acid (MCPBA). The Royal Society of Chemistry 2000.