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268557-54-6

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268557-54-6 Usage

Description

1-(2-bromoethyl)-4-octylbenzene, also known as 2-(4-Octylphenyl)ethyl Bromide, is an organic compound with a bromine atom attached to an ethyl group, which is further connected to a benzene ring with an octyl chain. This chemical structure endows it with unique properties that make it suitable for various applications in different industries.

Uses

1. Used in Pharmaceutical Industry:
1-(2-bromoethyl)-4-octylbenzene is used as a reagent for the synthesis of N-substituted iminosugar derivatives, which possess immunosuppressive activities. These derivatives are crucial in the development of drugs that can modulate the immune system, potentially leading to treatments for autoimmune diseases and organ transplant rejection.
2. Used in Chemical Synthesis:
In the field of chemical synthesis, 1-(2-bromoethyl)-4-octylbenzene serves as an intermediate or building block for the creation of more complex organic molecules. Its unique structure allows for further functionalization and modification, making it a valuable component in the synthesis of various specialty chemicals and materials.
3. Used in Material Science:
The compound's structural properties also make it a potential candidate for use in material science, where it could be employed in the development of novel materials with specific properties, such as improved thermal stability, chemical resistance, or enhanced mechanical strength.

Check Digit Verification of cas no

The CAS Registry Mumber 268557-54-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,6,8,5,5 and 7 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 268557-54:
(8*2)+(7*6)+(6*8)+(5*5)+(4*5)+(3*7)+(2*5)+(1*4)=186
186 % 10 = 6
So 268557-54-6 is a valid CAS Registry Number.

268557-54-6Relevant articles and documents

Synthesis of N-Substituted Iminosugar Derivatives and Evaluation of Their Immunosuppressive Activities

Lv, Zhuo,Song, Chengcheng,Niu, Youhong,Li, Qin,Ye, Xin-Shan

, p. 338 - 351 (2018/02/27)

It is important to find more effective and safer immunosuppressants, because clinically used immunosuppressive agents have significant side effects. A series of N-substituted iminosugar derivatives were designed and synthesized, and their immunosuppressive effects were evaluated by the CCK-8 assay. The results revealed that iminosugars 10 e and 10 i, that is, (3R,4S)-1-(4-heptyloxylphenylethyl)pyrrolidine-3,4-diol and (3R,4S)-1-[2-(2-chloro-4-(p-tolylthio)-phenyl-1-yl)ethyl]pyrrolidine-3,4-diol, respectively, exhibited the strongest inhibitory effects on mouse splenocyte proliferation (IC50=2.16 and 2.48 μm, respectively), whereas the iminosugars containing an amide group near the hydrophilic head (compounds 10 j–n) exhibited no inhibitory effects. Further studies revealed that the inhibitory effects on splenocyte proliferation may have come from the suppression of both IFN-γ and IL-4 cytokines. Our results suggest that synthetic iminosugars, especially compounds 10 e and 10 i, hold potential as immunosuppressive agents.

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