26965-15-1

Basic information

• Product Name: 5-Hexen-2-one, 3-phenyl-
• CAS NO: 26965-15-1
• Molecular Formula: C12H14O
• Molecular Weight: 174.243
• Mol File: 26965-15-1.mol
• Article Data: 19

Chemical Properties

• CAS DataBase Reference: 5-Hexen-2-one, 3-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Hexen-2-one, 3-phenyl-(26965-15-1)
• EPA Substance Registry System: 5-Hexen-2-one, 3-phenyl-(26965-15-1)

Safety Data

• Hazardous Substances Data: 26965-15-1(Hazardous Substances Data)

Upstream product

• 109-64-8 1,3-dibromo-propane 
• 103-79-7 1-phenyl-acetone 
• 24175-87-9 2-acetoxy-1-phenyl-1propene 
• 106-95-6 allyl bromide 
• 78303-39-6 [1-(1-aci-Nitro-ethyl)-but-3-enyl]-benzene 
• 705-60-2 1-phenyl-2-nitroprop-1-ene 
• 96-10-6 diethylaluminium chloride 
• 1730-25-2 allylmagnesium bromide 
• 917-54-4 methyllithium 
• 181513-65-5 1-(2-phenyl-1-selenoxo-4-pentenyl)pyrrolidine 
• 21087-29-6 trans-3-phenylprop-2-enyl chloride 
• 28483-60-5 Acetonyltributylstananne 
• 4784-77-4 (E/Z)-crotyl bromide 
• 96-09-3 styrene oxide 

Downstream Products

• 73222-64-7 (1-Isopropenyl-but-3-enyl)-benzene 
• 36293-43-3 (2R,3S)-3-phenylhex-5-en-2-ol 
• 36293-44-4 (2R,3R)-3-phenylhex-5-en-2-ol 
• 676548-10-0 (2S,3S)-3-phenylhex-5-en-2-ol 
• 676548-09-7 (2S,3R)-3-phenylhex-5-en-2-ol 
• 1173092-41-5 (3R)-3-phenyl-5-hexen-2-one 
• 2833-34-3 (S)-1-phenyl-3-buten-1-yl acetate 
• 181227-42-9 (+)-(R)-1-phenylbut-3-en-1-yl acetate 
• 132637-47-9 2-phenylhex-5-en-2-yl hydroperoxide 
• 120625-72-1 C₁₉H₁₈N₄O₆ 

Relevant articles and documents

Reactions of α,α-disubstituted selenoamides with organolithium reagents leading to unsymmetrical ketones

α,α-Disubstituted selenoamides were easily converted to unsymmetrical ketones in high yields by the reaction with alkyllithiums, whereas the reaction with alkynyllithium and methyl iodide gave α,β-unsaturated ketone and dialkynylamine.

The salt-free nickel-catalysed α-allylation reaction of ketones with allyl alcohol and diallylether

The nickel-catalysed α-allylation of ketones with allyl alcohol and diallylether has been performed under neutral conditions. As no base is involved, the products are synthesized without salts as side products. The dppf/Ni(cod)2 catalytic system in MeOH at 80 °C has been shown as the most effective reaction system to afford tetrasubstituted derivatives from various cyclic and acyclic ketones with one or two mobile protons. This process combined with a metathesis step yields spirocyclic compounds according to a salt free synthetic sequence.

Stereocontrolled Synthesis of Amino-Substituted Carbocycles by Pd-Catalyzed Alkene Carboamination Reactions

Amino-substituted alkylidenecyclopentanes were synthesized through a stereoselective intermolecular Pd-catalyzed alkene carboamination reaction between alkenyl triflates bearing a pendant alkene and exogenous amine nucleophiles. The reactions are effective with a range of different substrate combinations, and proceed with generally high diastereoselectivity. Use of (S)-tBuPhox as the ligand in reactions of achiral substrates provides enantioenriched products with up to 98.5:1.5 e.r.

One-pot method for α-phenylation of ketones using isoxazolidine and triphenylaluminum

The efficient one-pot umpolung α-phenylation of ketones via N-alkenylisoxazolidine is described. When the various ketones are treated with triphenylaluminum prepared from phenylmagnesium chloride and AlCl3 in the presence of isoxazolidine, the desired products are obtained in good to moderate yield. This method is equivalent to a direct α-arylation reaction of carbonyl groups.