270585-06-3

Basic information

• Product Name: 1-(2,5-dimethyl-phenyl)-5-isopropyl-3-methoxymethyl-1H-pyrazole
• CAS NO: 270585-06-3
• Molecular Weight: 258.363
• Mol File: 270585-06-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(2,5-dimethyl-phenyl)-5-isopropyl-3-methoxymethyl-1H-pyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,5-dimethyl-phenyl)-5-isopropyl-3-methoxymethyl-1H-pyrazole(270585-06-3)
• EPA Substance Registry System: 1-(2,5-dimethyl-phenyl)-5-isopropyl-3-methoxymethyl-1H-pyrazole(270585-06-3)

Safety Data

• Hazardous Substances Data: 270585-06-3(Hazardous Substances Data)

Upstream product

• 563-80-4 3-methyl-butan-2-one 
• 144712-26-5 1-methoxy-5-methylhexane-2,4-dione 
• 56737-78-1 2,5-dimethylphenylhydrazine hydrochloride 

Downstream Products

• 270585-16-5 4-{4-[1-(2,5-dimethyl-phenyl)-5-isopropyl-1H-pyrazol-3-yl]-4-oxo-butyryl}-benzoic acid methyl ester 
• 270585-13-2 1-[1-(2,5-dimethyl-phenyl)-5-isopropyl-1H-pyrazol-3-yl]-propenone 
• 270585-09-6 1-(2,5-dimethyl-phenyl)-5-isopropyl-1H-pyrazole-3-carbaldehyde 

Relevant articles and documents

Novel retinoic acid receptor α agonists: Syntheses and evaluation of pyrazole derivatives

We have designed and synthesized a series of pyrazole derivatives as candidate retinoic acid receptor (RAR) agonists. One of them, 4-[5-(1, 5-diisopropyl-1H-3-pyrazolyl)-1H-2-pyrrolyl]benzoic acid (11b), which possesses a 2,5-disubstituted pyrrole moiety, showed selective transactivation activity for the RARα receptor, and had highly potent cell-differentiating activity on HL-60 cells. (C) 2000 Elsevier Science Ltd. All rights reserved.