27059-40-1

Basic information

• Product Name: Benzene, (1-chlorobutyl)-
• CAS NO: 27059-40-1
• Molecular Formula: C10H13Cl
• Molecular Weight: 168.666
• Mol File: 27059-40-1.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Benzene, (1-chlorobutyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, (1-chlorobutyl)-(27059-40-1)
• EPA Substance Registry System: Benzene, (1-chlorobutyl)-(27059-40-1)

Safety Data

• Hazardous Substances Data: 27059-40-1(Hazardous Substances Data)

Upstream product

• 495-40-9 propiophenone 
• 13606-95-6 N-(pyridin-2-yl)butyramide 
• 5123-13-7 5,5-dimethyl-2-phenyl-1,3,2-dioxaborinane 
• 105854-98-6 1-phenyl-1-(phenylthio)butane 
• 104-51-8 1-butylbenzene 
• 75-71-8 Dichlorodifluoromethane 
• 187737-37-7 propene 
• 35364-99-9 α-chlorobenzyl methyl ether 
• 614-14-2 1-Phenyl-1-butanol 

Downstream Products

• 100874-73-5 N-butyl-1-phenylbutan-1-amine 
• 104-51-8 1-butylbenzene 
• 4397-69-7 (1-deuteriobutyl)benzene 
• 120357-05-3 4-(4-Fluorobenzoyl)-1-(4-phenylbutyl)piperidine 
• 84473-31-4 4-(Bromobutyl)benzene 
• 1560-06-1 1-phenyl-2-butene 
• 64985-90-6 meso-4,5-diphenyloctane 
• 93536-66-4 2-Methyl-4-phenyl-hepten-⁽²⁾ 
• 132515-10-7 (+/-)-4-phenyl-heptan-3-one 
• 6306-30-5 3-phenyl-2-hexanone 
• 42117-21-5 C₂₀H₂₆ 
• 42117-21-5 dl-4,5-diphenyloctane 
• 614-14-2 1-Phenyl-1-butanol 
• 74338-67-3 2-(1-Phenyl-butyl)-cyclohexanone 

Relevant articles and documents

Indium-Catalyzed Formal Carbon-Halogen Bond Insertion: Synthesis of α-Halo-α,α-disubstituted Esters from Benzylic Halides and Diazo Esters

One-carbon-unit insertion into carbon-halogen (C-X) bonds accompanied by the formation of a new C-X bond and carbon-chain elongation is a powerful synthetic method of complex organohalides. Herein, we developed an indium trihalide catalyzed formal insertion of diazo esters into a C-X (X = Cl, Br, I) bond. In the present system, the reactions of α-aryl diazo esters with benzylic chlorides, bromides, and iodides yielded α-chloro, α-bromo, and α-iodo esters, respectively.

α-Diimine-Niobium Complex-Catalyzed Deoxychlorination of Benzyl Ethers with Silicon Tetrachloride

α-Diimine niobium complexes serve as catalysts for deoxygenation of benzyl ethers by silicon tetrachloride (SiCl4) to cleanly give two equivalents of the corresponding benzyl chlorides, where SiCl4 has the dual function of oxygen scavenger and chloride source with the formation of a silyl ether or silica as the only byproduct. The reaction mechanism has two successive trans-etherification steps that are mediated by the niobium catalyst, first forming one equivalent of benzyl chloride along with the corresponding silyl ether intermediate that undergoes the same reaction pathway to give the second equivalent of benzyl chloride and silyl ether.

Desulfurative Chlorination of Alkyl Phenyl Sulfides

The chlorination of readily available secondary and tertiary alkyl phenyl sulfides using (dichloroiodo)benzene (PhICl2) is reported. This mild and rapid nucleophilic chlorination is extended to sulfa-Michael derived sulfides, affording elimination-sensitive β-chloro carbonyl and nitro compounds in good yields. The chlorination of enantioenriched benzylic sulfides to the corresponding inverted chlorides proceeds with high stereospecificity, thus providing a formal entry into enantioenriched chloro-Michael adducts. A mechanism implying the formation of a dichloro-λ4-sulfurane intermediate is proposed.