27693-42-1 Usage
Description
3,4-Dimethoxyphenyl 2-pyridyl ketone is an organic compound with a molecular structure that features a pyridine ring connected to a phenyl ring through a ketone group. The phenyl ring is substituted with two methoxy groups at the 3rd and 4th positions. 3,4-dimethoxyphenyl 2-pyridyl ketone has potential applications in the pharmaceutical and chemical industries due to its unique chemical properties and reactivity.
Uses
Used in Pharmaceutical Industry:
3,4-Dimethoxyphenyl 2-pyridyl ketone is used as an intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows it to be a valuable building block for the development of new drugs with potential therapeutic applications.
Used in Anti-inflammatory Applications:
3,4-Dimethoxyphenyl 2-pyridyl ketone has been synthesized and evaluated for its potential anti-inflammatory activity against carrageenan-induced edema in rat paws. It has shown more promising results compared to 2-benzoylpyridine (B209570), indicating its potential use as an anti-inflammatory agent.
Used in Bronchodilator Development:
3,4-Dimethoxyphenyl 2-pyridyl ketone is used as a reagent in the synthesis of 3,4-dihydroxyphenyl-(2-piperidyl)carbinols, which are cyclic adrenaline derivatives. These derivatives have been found to be potential powerful bronchodilators, making this compound an important component in the development of new treatments for respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD).
Check Digit Verification of cas no
The CAS Registry Mumber 27693-42-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,6,9 and 3 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 27693-42:
(7*2)+(6*7)+(5*6)+(4*9)+(3*3)+(2*4)+(1*2)=141
141 % 10 = 1
So 27693-42-1 is a valid CAS Registry Number.
InChI:InChI=1/C14H13NO3/c1-17-12-7-6-10(9-13(12)18-2)14(16)11-5-3-4-8-15-11/h3-9H,1-2H3
27693-42-1Relevant articles and documents
Cobalt(II)-based Metalloradical Activation of 2-(Diazomethyl)pyridines for Radical Transannulation and Cyclopropanation
Roy, Satyajit,Das, Sandip Kumar,Chattopadhyay, Buddhadeb
, p. 2238 - 2243 (2018/02/19)
A new catalytic method for the denitrogenative transannulation/cyclopropanation of in-situ-generated 2-(diazomethyl)pyridines is described using a cobalt-catalyzed radical-activation mechanism. The method takes advantage of the inherent properties of a CoIII-carbene radical intermediate and is the first report of denitrogenative transannulation/cyclopropanation by a radical-activation mechanism, which is supported by various control experiments. The synthetic benefits of the metalloradical approach are showcased with a short total synthesis of (±)-monomorine.
A facile synthetic route for 2-pyridyl derivatives: direct preparation of a stable 2-pyridylzinc bromide and its copper-free and pd-catalyzed coupling reactions
Kim, Seung-Hoi,Rieke, Reuben D.
supporting information; experimental part, p. 5329 - 5331 (2009/12/06)
Direct preparation of 2-pyridylzinc bromide has been developed. Interestingly, the subsequent coupling reactions with acid chlorides have been carried out without any transition metal catalyst. 2-Pyridylaryl compounds, symmetrical and unsymmetrical 2,2′-b
Aroylcrownethers
-
, (2008/06/13)
Aroylcrownethers are complexing agents for metals, dispersing agents for carbon black and preferred ones are antiviral agents. Examplary is 4'-benzoylbenzo-18-crown-6 of the formula STR1
